State and municipal people’s governments, provincial committees, offices, departments and bureaus:

"Yunnan Province" 14 th Five-Year Plan "for the Innovation and Development of Biomedical Industry has been agreed by the provincial people’s government and is hereby issued to you, please implement it carefully.

General Office of Yunnan Provincial People’s Government

March 17, 2022

(This piece is publicly released)

In order to accelerate the innovation and development of the biomedical industry, this plan is formulated according to the 14th Five-Year Plan for National Economic and Social Development in Yunnan Province and the Outline of Long-term Objectives for the Year 2035, combined with the reality of our province.

I. Development Status and Situation

(A) Development effectiveness

During the "Thirteenth Five-Year Plan" period, the provincial party committee and the provincial government conscientiously implemented the spirit of the important speech of the Supreme Leader General Secretary on his inspection of Yunnan, and on the basis of continuously building eight key industries and world-class "three cards", put forward the strategic deployment of focusing on cultivating five trillion-level pillar industries and eight billion-level advantageous industries and building a modern industrial system. Biomedical industry, as a strategic emerging industry with a focus of 100 billion yuan in our province, has steadily expanded its scale, significantly enhanced its innovation ability, increasingly optimized its policy environment, and continuously improved its economic benefits. Its operating income increased from 124.109 billion yuan in 2015 to 252.145 billion yuan in 2020, with an average annual growth rate of 15.23%, and its added value increased from 36.587 billion yuan in 2015 to 73.14 billion yuan in 2020. The average annual growth rate reached 14.86%, the business income and added value doubled, and a research and production system of biotechnological drugs focusing on vaccines was gradually formed, and a whole industrial chain development system of natural drugs (ethnic Chinese medicines) featuring proprietary Chinese medicines, Chinese herbal pieces, extracts and health products was established.

In 2020, the province’s Chinese herbal medicine planting (breeding) industry will realize an operating income of 51.611 billion yuan; The biomedical manufacturing industry realized an operating income of 59.592 billion yuan; The biomedical commerce and trade industry realized an operating income of 140.942 billion yuan. There are 163 pharmaceutical manufacturing enterprises above designated size (including 1 enterprise with operating income exceeding 10 billion yuan and 5 enterprises with 1-10 billion yuan). There are 48 varieties with sales income exceeding 100 million yuan (including 5 varieties exceeding 1 billion yuan and 4 varieties with 500-1 billion yuan). Up to now, there are 9 biomedical enterprises listed on the main board and growth enterprise market in the province.

1. The biotechnology pharmaceutical industry has made breakthrough development.

In 2020, the province’s biological products manufacturing industry above designated size represented by vaccines achieved an operating income of 5.357 billion yuan, accounting for 15.6% of the operating income of pharmaceutical manufacturing industry above designated size. There are 13 vaccine varieties on the market, and the operating income of vaccine enterprises has increased from 800 million yuan in 2009 to 4.8 billion yuan in 2020, and the biotechnology drug industry has made breakthrough progress. The inactivated enterovirus 71 vaccine independently developed by the Institute of Medical Biology, Chinese Academy of Medical Sciences was launched in December 2015, and the annual operating income of a single variety was nearly 2 billion yuan. The 23-valent pneumococcal polysaccharide vaccine developed by watson biological was launched in July 2017, with an operating income of 688 million yuan in 2020; The first trivalent pneumococcal polysaccharide conjugate vaccine in China and the second trivalent pneumococcal polysaccharide conjugate vaccine in the world went on the market in April 2020, with an operating income of 1.658 billion yuan in the first year, and the market prospect is considerable. Some traditional pharmaceutical companies and scientific research units have accelerated the layout and development of biotechnological drugs. Suparutide injection, a long-acting hypoglycemic drug developed by Kunyao Group, has obtained clinical approval, and Sino Pharmaceutical has carried out research on new drugs of humanized CD22 antibody immunotoxin 1.1.

2 Chinese medicine (ethnic medicine) industry scale

In recent years, the traditional Chinese medicine (ethnic medicine) industry in our province has become the main force to promote the development of biomedical industry from small to large and from weak to strong. 60 "Hometowns of Yunyao" and 103 "Pharmaceutical Parks" have become the new force to improve the quality and brand of Chinese herbal medicines. In 2020, the main business income of planting (breeding) and product processing of Chinese herbal medicines in the province will exceed 100 billion yuan, among which the processing and manufacturing of Chinese herbal medicines above designated size, such as proprietary Chinese medicines, Chinese herbal pieces, extracts and health products, will achieve an operating income of about 48 billion yuan, accounting for over 80% of the main business income of biomedical industries above designated size. The planting area of Chinese herbal medicines exceeds 9 million mu, the planting area of 15 varieties of Chinese herbal medicines, such as Panax notoginseng, Paris polyphylla, Dendrobium, Amomum villosum and Radix Aucklandiae, exceeds 100,000 mu, and the standardized planting base of Chinese herbal medicines covers an area of 1.46 million mu, including 22,000 mu of green certification base and 126,000 mu of organic certification base. Sanqi, Erigeron breviscapus industry has formed a whole industrial chain layout of planting, processing, R&D and production, which has played a very prominent role in demonstrating the development of traditional Chinese medicine industry in the province. Panax notoginseng industry has achieved standardization and standardized planting, and developed relatively complete back-end products such as decoction pieces, preparations and health products, which has become a big variety second only to ginseng. The planting area of the whole province is about 400,000 mu, and the agricultural output value is about 6 billion yuan. A number of Chinese patent medicines and injections such as Panax notoginseng decoction pieces, Xuesaitong soft capsules, Xuesaitong for injection (freeze-dried powder injection), Xuesaitong tablets, Xuesaitong capsules, Panax notoginseng saponins and Xuesaitong injection, etc.

3. The chemical medicine industry has developed steadily.

In 2020, the chemical preparation manufacturing industry and the chemical raw material medicine manufacturing industry above designated size will realize an operating income of 3.52 billion yuan, accounting for 10.2% of the pharmaceutical manufacturing industry above designated size. Initially gathered a number of chemical pharmaceutical enterprises such as Jida Pharmaceutical, Baker Norton, Haobang Pharmaceutical, Sino Pharmaceutical, Longhai Pharmaceutical and Guiyan Pharmaceutical; Longjin Pharmaceutical, Haobang Pharmaceutical and Plant Pharmaceutical cooperated with Indian generic drug companies to actively introduce Indian generic drug varieties to Yunnan; Nine varieties, including amoxicillin capsules, chlorphenamine maleate tablets and ambroxol hydrochloride injection, passed the consistency evaluation of chemical generic drugs.

4. Remarkable achievements have been made in biomedical science and technology innovation.

Driven by scientific and technological innovation, the biomedical industry has gradually embarked on a high-quality development track. Sabin inactivated poliomyelitis vaccine, EV71 inactivated enterovirus vaccine, 13-valent pneumococcal polysaccharide conjugate vaccine and other fist products have been listed one after another, and some varieties are undergoing WHO pre-certification; Covid-19 inactivated pneumonia vaccine, F gene mumps live attenuated vaccine, nine-valent human papillomavirus (HPV) vaccine, rotavirus inactivated vaccine and tetravalent meningococcal polysaccharide conjugate vaccine are in the clinical research stage, which has provided strong support for the rapid development of the vaccine industry during the Tenth Five-Year Plan. Ten innovative drugs, such as KPCXM18, a natural medicine for treating ischemic stroke, Duanjin Jiedu Capsule, a 6-class Chinese medicine, Suparutide injection, and a 1.1-class new drug of bungarus multicinctus venom, were approved by the national drug clinical approval. Winona series products, with authentic Yunnan medicinal materials as the main raw materials, have developed into an important functional skin care brand in China. "Key Technology Creation and Industrial Application of Comprehensive Development of Panax notoginseng" won the second prize of National Science and Technology Progress Award, "Key Technology and Application of Standardization and Industrial Development of Panax notoginseng" won the first prize of Yunnan Science and Technology Progress Award, and three standards of Panax notoginseng, seeds and seedlings and Gastrodia elata passed the international quality standard certification. Panax notoginseng saponins and breviscapine have passed GRAS (generally considered safe) certification recognized by FDA, and entered the catalogue of American botanical medicine raw materials;Tongshu capsule and Xuesaitong soft capsule were approved by FDA to carry out phase II clinical research.

Around the great demand of the development of biomedical industry, a number of R&D service platforms have been built, such as Yunnan Biovaccine Technology Innovation Center, Yunnan Drug Non-clinical Safety Evaluation Research Center, Yunnan Natural Drug Activity Screening and Evaluation Center, Yunnan Stem Cell and Regenerative Medicine Research Center, Yunnan Flower Aromatic Health Products R&D Center, and Yunnan Chinese Medicine Seed Breeding R&D Center. By the end of the 13th Five-Year Plan, there were 47 provincial key laboratories in the biomedical field, 20 engineering technology research centers, 19 engineering research centers, 10 clinical medical research centers and 4 academicians of the two academies in the province, and 12 provincial science and technology leaders were trained, 54 provincial high-level talents were introduced, 4 high-level innovation and entrepreneurship teams were introduced, 553 provincial young and middle-aged academic and technological leaders and 553 provincial innovative talents were trained.

5. Bio-pharmaceutical industry has achieved initial results by attracting big and strong players.

Yunnan Baiyao Group introduced social capital to complete the mixed reform, and the development of the group entered the fast lane; China Resources Sanjiu acquired Kunming Shenghuo Pharmaceutical, and the company’s operating income increased significantly; Guizhou Bailing invested in Yunnan plant pharmaceutical industry, focusing on characteristic products, optimizing product structure, and implementing large-variety brand strategy. The scale of the enterprise has maintained rapid growth for many years. Well-known enterprises inside and outside the province, such as Sinopharm Group, Shanghai Pharmaceutical Group, Guangzhou Pharmaceutical Group, Tasly Pharmaceutical, Kangenbei Pharmaceutical, Shenwei Pharmaceutical, New Green Pharmaceutical, Beijing Tongying, Fangsheng Pharmaceutical, Jilin Xingshen, Hong Kong Juzhang and Shenzhen Botton, have landed in Yunnan and actively participated in the healthy development of the biomedical industry.

(B) Advantages and shortcomings

1. Location advantage

Yunnan has outstanding geographical advantages. It is adjacent to Guizhou and Guangxi in the east, Sichuan in the north, Tibet in the northwest, and Myanmar, Laos and Vietnam in the west and south. It is an important channel connecting South Asia, Southeast Asia and the Indian Ocean region, and an important intersection of the "Belt and Road" construction and the national development strategy of the Yangtze River Economic Belt. The biomedical industry has a huge potential market, which can be built on the basis of vaccines and traditional Chinese medicine (ethnic medicine)

2. Resource advantages

Yunnan has obvious three-dimensional climate characteristics, many types, beautiful mountains and rivers, pleasant climate and outstanding biodiversity characteristics. It is known as the "plant kingdom", "animal kingdom", "microbial kingdom", "hometown of medicinal materials" and "treasure house of biological genes", and is the province with the richest biological resources, natural medicines and ethnic medicine resources in China. According to the statistics of the third national survey of traditional Chinese medicine resources, there are 6,559 kinds of traditional Chinese medicine resources in the province, accounting for 51.4% of the total number of kinds in the country, more than 2,000 kinds of ethnic medicine resources and more than 10,000 folk prescriptions.

3. Advantages of industrial base

Notoginseng Radix, Rhizoma Paridis Yunnanensis, Erigeron breviscapus, Dendrobium candidum, Fructus Amomi, Rhizoma Gastrodiae, Poria Yunensis, Radix Angelicae Sinensis, Radix Aucklandiae, Radix Gentianae Yunnanensis and other "Top Ten Yunyao" brand medicinal materials have excellent quality and are widely recognized in the industry. It has built a domestic raw material base for high-quality natural medicines and health products. The large varieties of Yi medicine represented by Yunnan Baiyao, the unique ethnic medicines such as Dai and Naxi, and the unique ethnic medical technologies such as Dai medicine, which are in the same strain as the traditional medical systems of neighboring countries, provide rich ethnic medical resources for the innovation, inheritance and development of traditional Chinese medicine and the opening up of markets for South Asian and Southeast Asian countries. Gu Fangzhou, known as the "father of polio vaccine in China", engaged in the research of live attenuated polio vaccine in Yunnan, established the method of isolation and finalization of polio virus, formulated the trial production and safety standards of live polio vaccine, and formulated the "Rules for the manufacture and verification of live polio vaccine", which guided the production and identification of billions of vaccines in China and laid a solid foundation for the rapid development of vaccine industry in our province.

4. Shortcomings of rapid industrial development

First, the industry is small in scale and weak in competitiveness. The overall scale of Yunnan’s biomedical industry is small. Among the top 500 main business incomes of the national pharmaceutical industry, there are only 10 in Yunnan. The overall competitiveness of the biomedical industry, which is dominated by traditional Chinese medicine, is weak, especially affected by the national medical reform policies such as the catalogue of auxiliary drugs of traditional Chinese medicine, the catalogue of medical insurance, and the consistency evaluation of traditional Chinese medicine injections. The scale of biomedical manufacturing industry has declined slightly for two consecutive years.

Second, the industrial structure is not excellent and the industrial chain is incomplete. The development of standardized planting (breeding) bases of Chinese herbal medicines lags behind, the phenomenon of small varieties of Chinese herbal medicines is prominent, the research foundation is uneven, and the competitiveness of products is generally weak; Vaccines are the main biotechnological drugs, but the pipelines of antibody drugs, biological similar drugs, cell products, blood products and other products are not rich, and the upstream and downstream supporting industries are basically blank; Small amount of chemicals, lack of original research drugs and high-end generic drugs; The development level of medical devices and veterinary drugs is low.

Third, the core competitiveness of enterprises is weak, and the degree of specialization of the park is low. There are few well-known enterprises and leading enterprises, leading enterprises are not aware of advanced layout and innovative R&D activities, and the industry is not leading enough; Insufficient investment in research and development, lack of influential and innovative varieties, and weak core competitiveness; The level of professional development of biomedical industrial park is not high, the supporting system is not perfect, and the public R&D and service capabilities are weak.

Fourth, innovation ability is not strong, and high-level talents are lacking. The research and development system of new drug creation is imperfect, the resources are scattered, and the technical level is not high, which does not match the needs of the industrial chain; Lack of forward-looking scientific research ability for common technologies, key technologies and cutting-edge technologies needed for rapid industrial development; There are few innovative products in other industries except vaccines; The linkage between enterprises and scientific research institutions is not close, and the contradiction between supply and demand in the transformation of scientific and technological achievements is prominent; Lack of high-level R&D innovation centers and insufficient public R&D service platforms such as drug safety evaluation (GLP), drug clinical evaluation (GCP) and contract R&D institutions (CRO); There is a serious shortage of high-level innovative talents, management talents and teams.

Fifth, brand building is not enough, and market development ability is weak. Enterprises are weak in coping with industrial policies such as medical reform, drug review and approval, and drug production supervision, and weak in market cultivation and brand building of their own products; There is a lack of systematic publicity highlighting the advantages and characteristics, insufficient excavation of superior Chinese herbal medicine varieties, time-honored traditional Chinese medicine and ethnic medicine culture, and weak brand building and market promotion of "Yunyao".

(3) Opportunities and challenges

1. Health needs are increasing.

With the increase of sub-health population and the acceleration of population aging, people’s demand for health products has increased rapidly; The demand for health consumption has changed from medical treatment to disease prevention, health care and health promotion; The national new medical reform plan puts the prevention and control of diseases in the first place, and pays more attention to "preventing diseases before they occur". Traditional Chinese medicine (ethnic medicine) will be promising.

2. Building a domestic and international dual cycle will bring new opportunities for industrial development.

The COVID-19 epidemic has had a great impact on the global industrial chain and supply chain. It is an inevitable requirement to maintain a stable and healthy economic development by adjusting the economic development path, opening up the international circulation, smoothing the domestic circulation, coordinating development and security, enhancing the autonomy, sustainability and resilience of economic development. Seize the development opportunities brought by the Regional Comprehensive Economic Partnership Agreement (RCEP), make full use of Yunnan’s geographical advantages in connecting South Asia, Southeast Asia and the Indian Ocean region, and exchange the traditional medicine with neighboring countries, realize the smooth connection with the biomedical industry in South Asia and Southeast Asia, and accelerate the construction of a new international and domestic dual-cycle development pattern.

3. The epidemic situation in COVID-19 affected the development pattern of pharmaceutical industry.

After the outbreak of COVID-19, COVID-19’s vaccine research and development and production have become the focus of international competition in the field of biotechnology drugs, which puts forward new requirements for the corresponding research and development technology system, experimental evaluation, manufacturing capacity level and organizational management efficiency. With the development of modern biotechnology such as genetic engineering, cell engineering, tissue engineering, biosynthesis, bioinformatics and precision medicine, biotechnological drugs such as vaccines and antibody drugs have become the main direction of the transformation and upgrading of the biomedical industry. The competitive advantages of prescription and medicine represented by "three drugs and three parties" are prominent, and the modern innovative Chinese medicine with clear mechanism of action and definite clinical effect has obvious competitiveness. The demand for medical materials represented by ventilators, testing reagents, medical masks and protective clothing has surged, which has promoted the development of the medical device industry.

4. Competition in domestic pharmaceutical industry is becoming increasingly fierce.

All provinces (autonomous regions and municipalities) take biomedicine as a priority industry, and Beijing, Shanghai, Jiangsu, Guangdong and other provinces (municipalities) have been at the forefront of the country by virtue of their own geographical, policy, talent and technical advantages; Shandong, Sichuan, Hubei, Jiangxi and other provinces have also accelerated the pace of industrial development, and the competition between regions has become increasingly fierce. The reorganization of enterprises in the industry is frequent, and super-large enterprises are constantly emerging. The development trend of agglomeration is obvious, full of opportunities and challenges.

5. The medical reform policy forces the pharmaceutical industry to develop with high quality.

The research and development, production and sales of pharmaceutical products are highly dependent on policy factors, and the industrial development is deeply influenced by policy regulation. The continuous adjustment of various policies, such as drug supervision, the catalogue of traditional Chinese medicine auxiliary drugs and the new medical insurance catalogue, has prompted pharmaceutical enterprises to increase investment in research and development, take a higher quality development path, change from extensive development to refined development mode, and change products from imitation to original innovation. At the same time, information technology represented by mobile medical care, cloud computing, big data and Internet of Things has begun to penetrate into all aspects of the biomedical industry.

6. Competition for innovative drugs has intensified.

At present, the research and development of major innovative drugs are still led by well-known multinational companies, and the competition for technology, talents and funds in the biomedical industry is extremely fierce. Large pharmaceutical companies focus on developing innovative drugs for clinical value in the fields of biotechnology drugs and chemical drugs, while expanding new indications of existing products and expanding upstream and downstream business chains. Pharmaceutical companies with obvious competitive advantages in core products, diversified products and outstanding R&D capabilities will have stronger competitiveness and anti-risk ability. The global vaccine industry presents an oligopoly pattern, with the top 10 companies accounting for 95.7% of the total vaccine market share, and the four vaccine giants GSK (GlaxoSmithKline), Merck, Sanofi and Pfizer accounting for about 80% of the total market share. In the future, the global vaccine market has great growth potential and will grow rapidly with a compound annual growth rate of 10%. The rapid development of frontier technologies such as gene therapy and cell therapy is expected to form major innovative drugs and new supporting technologies. The patents of the top 10 original drugs in global sales, such as Hummel, Merlot and Avastin, are about to expire, and generic drugs and bio-similar drugs are expected to usher in new opportunities. From the national situation, the major achievements of new drug research and development are mainly concentrated in Beijing, Shanghai, Jiangsu and other places, and innovative enterprises led by new drug research and development, such as Hengrui Pharma and Wuxi PharmaTech, have a strong development momentum.

Second, the development ideas, principles and objectives

(A) development ideas

Guided by the Supreme Leader’s Socialism with Chinese characteristics Thought in the New Era, we will fully implement the spirit of the 19th National Congress of the Communist Party of China and the previous plenary sessions of the 19th National Congress, thoroughly study and implement the spirit of the important speech of the Supreme Leader’s General Secretary on his visit to Yunnan, conscientiously implement the decision-making arrangements of the provincial party committee and government, grasp the new development stage, implement the new development concept, serve and integrate into the new development pattern, adhere to the problem-oriented, goal-oriented and result-oriented, take innovation as the core, quality as the foundation, and take enterprises as the main body. Market-oriented, focusing on the three key areas of biotechnological drugs, modern Chinese medicine and health products, we will focus on attracting investment accurately, strengthening the main body of enterprises, enhancing innovation ability, building industrial clusters, promoting industrial development with engineering measures, building domestic first-class R&D and production bases of biological vaccines and modern Chinese medicine, domestic top-quality raw materials bases of natural drugs and health products, and biomedical trade bases facing South Asia and Southeast Asia, forming an industrial cluster with important influence in the country, and realizing the high-quality development of Yunnan biomedical industry.

(2) Basic principles

1. Innovation-driven, quality-improved development

Around the industrial chain, deploy innovation chain, build a batch of high-level public service platforms and professional R&D platforms, break through a batch of technologies, reserve a batch of achievements, develop a batch of products and transform a batch of achievements, and promote the high-quality development of Yunnan biomedical industry.

2. Based on advantages and outstanding features

Based on the advantages of Yunnan’s location, ecology, environment, resources and nationality, we will highlight the characteristics of biological vaccines, authentic medicinal materials, ethnic medicine, classic and famous prescriptions, proven prescriptions and cell technology, strengthen product quality and standards, and accelerate industrial transformation and upgrading.

3. Government guidance and market dominance

Innovate institutional mechanisms, rationally allocate resources, break through policy bottlenecks, cultivate and expand market players, release enterprise vitality and market potential, and build a sound market system and policy system.

4. Open cooperation and push forward together.

Improve the soft and hard environment, expand the domestic and foreign markets, and support local enterprises to become bigger and stronger; Introduce well-known enterprises and scientific research achievements to expand the increment; Attracting scientific research institutes from outside the province to develop in Yunnan, jointly cultivating talents, focusing on R&D and innovation, and forming a strong synergy to promote industrial development.

(III) Overall objectives

By 2025, the operating income of the biomedical industry will achieve the goal of "ensuring four guarantees and competing for five", that is, it will reach 400 billion yuan and strive to reach 500 billion yuan, with an average annual growth rate of more than 10%. Among them, the biomedical manufacturing industry will achieve an operating income of more than 150 billion yuan, with an average annual growth rate of more than 20%. The added value of biomedical industry reached 120 billion yuan, with an average annual growth rate of more than 10%. Strive for the biological vaccine industry to achieve the number and value of batch issuance. Facing 2035, we will focus on key markets, increase promotion, actively tap the domestic market, vigorously explore the South Asia and Southeast Asia markets, further enhance the influence and market share of the brand "Yunyao", and build Yunnan into a biomedical R&D innovation and product production and trade center with distinctive characteristics of serving the whole country and radiating South Asia and Southeast Asia, and build an industrial cluster with important influence in the country.

-do it on a large scale. By 2025, we will cultivate more than one enterprise (group) with operating income exceeding 50 billion yuan, more than five enterprises (groups) exceeding 10 billion yuan, more than five enterprises (groups) exceeding 5 billion yuan, more than 20 enterprises (groups) exceeding 1 billion yuan and more than 70 enterprises exceeding 100 million yuan.

-strengthen varieties. By 2025, more than 10 varieties with sales income exceeding 1 billion yuan and more than 60 varieties with sales income exceeding 100 million yuan will be cultivated.

-do an excellent structure. By 2025, the leading development of biotechnological drugs will be realized, modern Chinese medicine (ethnic medicine) will be upgraded and developed, dual-use products for medicine and food will develop by leaps and bounds, and chemical drugs and medical devices will make breakthroughs.

-fill in the short board. We will build and upgrade a number of public R&D and service platforms around biotechnology drugs, modern Chinese medicine and chemical drugs, break through a number of key core technologies, and develop a number of competitive and innovative products.

Third, key tasks

Around the biomedical industry chain, deploy innovation chain, promote the organic integration of industry chain and policy chain, innovation chain, capital chain, supply chain, talent chain and value chain, focus on key core technologies, fill the shortcomings of the platform and increase high-quality varieties. Strengthen leading enterprises and enhance manufacturing capacity. Optimize the industrial layout, strengthen the construction of the park, and form industrial agglomeration. Enhance the brand of "Yunyao", revitalize the stock, introduce increments, expand the total amount, and realize the high-quality development of the biomedical industry.

(1) Strengthen varieties and accelerate the transformation and upgrading of biomedical manufacturing.

Give priority to the development of biological vaccines, modern Chinese medicines (ethnic medicines), Chinese herbal pieces and chemical medicines, vigorously develop biotechnological medicines such as antibody medicines, gene technology, cell therapy and blood products, as well as health products, detection and diagnosis reagents, medium and high-end medical devices, strengthen the research and innovation of biotechnological medicines, modern Chinese medicines, natural medicines, generic medicines, new preparations and health care products, and support the internationalization of vaccines, modern Chinese medicines and medical devices. Focusing on increasing investment in scientific and technological innovation, building a number of well-known enterprises and brand products, introducing large enterprises and groups, encouraging enterprises to acquire and merge, and promoting international development, we will promote digital and intelligent manufacturing and accelerate the transformation and upgrading of biomedical manufacturing.

1. Key development areas

(1) Biotechnology drugs focusing on vaccines

The biotechnology pharmaceutical industry focusing on vaccines is the fastest-growing field in the biomedical industry in our province, and efforts should be made to improve the upstream and downstream industrial chains, enhance the research and development capacity of new vaccines, accelerate the construction of a rapid response system for major infectious diseases, strengthen frontier basic research, and enrich product pipelines.

Focus on Kunming and Yuxi to build biotechnology pharmaceutical industrial bases focusing on vaccines, and vigorously develop new biological vaccines, antibody drugs, biological analogues, cell preparations, blood products such as albumin, coagulation factors and immunoglobulin, and other new products of proteins, peptides and nucleic acids. Enlarge and strengthen the existing biotechnology drug enterprises, encourage vaccine enterprises to build digital and intelligent production lines, and improve the production technology level. Guide enterprises in the province to build, acquire and merge R&D institutions at home and abroad, build a quality system, R&D system and production technology system that are in line with international standards, promote the international registration and WHO pre-certification of biological vaccine products, build a vaccine production and supply base that meets international quality standards and a leading domestic monoclonal antibody drug industry base, increase open cooperation with South Asia, Southeast Asia, Africa, Europe and the United States, and open up markets in South Asia, Southeast Asia and the Indian Ocean Rim.

Traditional vaccines: enterprises are encouraged to develop univalent vaccines, multivalent vaccines and multiplex vaccines with attenuated, detoxified and inactivated products based on pathogenic microorganisms and their metabolites, so as to promote the secondary development and upgrading of biological vaccines.

New vaccines: break through the key core technologies such as efficient genetic engineering construction technology of virus species and strains, screening research technology of pathogen antigen components, bacterial polysaccharide-protein binding technology, large-scale animal cell culture technology, new vaccine adjuvant technology, genetic engineering technology, genetic engineering recombination technology, non-human primate model evaluation, and carry out research and development and transformation of new vaccines such as nucleic acid vaccine, synthetic peptide vaccine, genetic engineering vaccine and recombination vaccines. Increase the forward-looking research and development of mRNA technology in the prevention and treatment of infectious diseases, AIDS, genetic diseases, rare diseases, tumors and other major diseases.

Antibody, protein and nucleic acid drugs: develop monoclonal antibody drugs, neutralizing antibodies, bispecific antibodies, antibody-coupled drugs (ADC), biological analogues, recombinant protein drugs, polypeptide drugs and nucleic acid drugs for diseases such as tumor, immune system, cardiovascular and cerebrovascular diseases and infections.

Animal vaccines: Encourage the research and development of veterinary vaccines such as Class A epidemic vaccines, multi-animal co-morbid vaccines, vaccines for cattle and sheep, vaccines for pigs, vaccines for poultry, and vaccines for pets.

Cell preparation: within the scope permitted by policies and regulations, encourage and standardize the research and development of cell therapy products including stem cells and immune cells; We will carry out research on a series of standards and technical systems such as preparation, quality inspection and safety evaluation of clinical-grade cell products and derivatives, improve their safety, effectiveness and quality controllability, and accelerate the research on clinical application norms of cell therapy.

Blood products: introduce and develop blood products, focusing on the development of coagulation factors, thrombin, human albumin, human fibrinogen, immunoglobulin and other products. Within the scope permitted by the policy, the layout of plasma raw materials will be increased by adding plasma collection stations.

Other biotechnologies: Accelerate the construction of a synthetic biotechnology innovation system, support the research on genome design and synthesis, and provide technical support for basic research on new biological treatment methods, vaccines, materials and disease control.

Make use of the advantages of genetic resources in our province to develop the biomedical industry of non-human primates and carry out research on the protection and rational utilization of human genetic resources; Carry out research on transplant organ cultivation technology and xenotransplantation technology.

(2) Modern Chinese medicine represented by formula granules.

Focus on the quality upgrade, secondary development, new indications mining, economic evaluation, clinical value-oriented research on safety and clinical efficacy evaluation of traditional Chinese medicine, and innovative drug development of traditional Chinese medicine, and make efforts in the research on local standards of characteristic Chinese herbal pieces, quality standards that meet the requirements of Pharmacopoeia, effectiveness and safety evaluation, production process improvement, and automation, intelligence and information construction of production and processing.

Focus on Kunming, Yuxi, Chuxiong, Dali, Wenshan, Baoshan, Pu ‘er, Honghe and other cities to develop modern Chinese medicine. On the basis of medicinal animal and plant resources such as Panax notoginseng, Erigeron breviscapus, Gastrodia elata, Paris polyphylla, Periplaneta americana, leech, etc., and taking the development of characteristic ethnic medicines such as Yi medicine and Dai medicine as a breakthrough, we will speed up the cultivation of large varieties of modern Chinese medicine (ethnic medicine) preparations, create a number of brand products, and make Yunnan medicine industry bigger and stronger. Based on classic prescriptions, proven prescriptions and hospital preparations, we will develop innovative Chinese medicine (ethnic medicine) and epidemic prevention preparations covering the whole life cycle of prevention, treatment and rehabilitation for the prevention and treatment of major diseases such as malignant tumors, cardiovascular and cerebrovascular diseases, emerging infectious diseases and AIDS. Guided by clinical value, we will carry out material basic research, safety evaluation of traditional Chinese medicine and clinical efficacy research, and explore the construction of a three-in-one evidence system of "Chinese medicine theory-human experience-clinical trial" for the research and development of new traditional Chinese medicine. Adopt modern biotechnology, advanced pharmaceutical technology and preparation technology to promote the application of biocatalysis and transformation, refining, extraction and separation in the research and development of modern Chinese medicine.

In Kunming, Chuxiong, Wenshan, Zhaotong, Pu ‘er, Baoshan, Lijiang and other major producing areas, the production base of Chinese herbal pieces will be laid out, with the focus on building Chuxiong into a national first-class industrial base of Chinese herbal formula granules. Form more than 10 brand enterprises producing Chinese herbal pieces and local standards for formula granules of more than 100 varieties. Strengthen cooperation with state-level research institutions and well-known domestic enterprises, carry out research on quality standards of traditional Chinese medicine formula granules and upgrade the processing and production technology, and establish a quality standard system, a safety evaluation system and a clinical trial research system for traditional Chinese medicine decoction pieces that meet the requirements of People’s Republic of China (PRC) Pharmacopoeia and international standards. Carry out the equivalent test and production technology research of formula granules, and establish the processing technology and quality evaluation method of traditional Chinese medicine decoction pieces combined with modern science and technology. Develop new modern technologies, equipment and facilities such as extraction, concentration, drying and granulation, apply blockchain traceability technology to improve online quality control, establish a traceability system for processing and production of Chinese herbal pieces, and build a number of intelligent production lines of Chinese herbal pieces with advanced technology and strict quality control.

We will build a research center for ethnic medicine focusing on Yi medicine, Dai medicine and Tibetan medicine, systematically excavate and sort out ethnic medicine documents of Yi, Dai, Tibetan, Naxi, Wa and Hani nationalities, and carry out clinical application of traditional ethnic medicine therapy and its ancillary products and theoretical research on ethnic medicine. Relying on ethnic medicine resources, develop external preparations. Strengthen the research and development and clinical application of preparations in ethnic medicine hospitals, and carry out research and development of new ethnic medicine with clear mechanism, high technology content and reliable curative effect.

Build a characteristic industrial cluster of Sanqi, and build Sanqi into the first brand of traditional Chinese medicine in China. We will build a Sanqi industrial innovation consortium with enterprises as the main body, and gather superior resources inside and outside the province to carry out key technology research and transformation and application of achievements. Develop innovative drugs for prevention, treatment and rehabilitation of cardiovascular and cerebrovascular diseases; Focusing on the large varieties and exclusive varieties of traditional Chinese medicine (ethnic medicine) such as Sanqi series and Dengzhanhua series, we will increase the re-evaluation after listing and the secondary development of "new use of old drugs", and carry out research on the combination of traditional Chinese and western medicine such as "Xuesaitong+aspirin"; Strengthen the biosynthesis and application of panax notoginseng saponins, scutellarin, Paris polyphylla saponins and other extracts; Carry out research on the processing technology and technology of traditional Chinese medicines such as Panax Notoginseng while fresh, and formulate standards for new-type decoction pieces such as formula granules and powder decoction pieces of characteristic varieties such as Panax Notoginseng and Gastrodia elata which meet the standards of People’s Republic of China (PRC) Pharmacopoeia; To study and formulate EU Pharmacopoeia standards for Sanqi formula granules, panax pseudo-ginseng and other products, so as to enhance the international popularity and influence of Sanqi.

Regional cooperation in the research and development of traditional Chinese medicine (ethnic medicine) should be carried out for South Asia and Southeast Asia, international multi-center clinical trials and international registration of traditional Chinese medicine preparations with good clinical effect and clear mechanism of action should be carried out, and a modern standard production system and quality evaluation system of traditional Chinese medicine should be constructed according to international standards.

(3) Health products based on natural extracts.

Continue to strengthen the research on the material basis of effective active ingredients of animals and plants, increase the development and application of extracts, strengthen the development of high-quality health products, and cultivate brand products with market competitiveness and scale effect.

Focus on Kunming, Yuxi, Chuxiong, Pu ‘er, Xishuangbanna, Lijiang, Wenshan and other cities to build health product research and development and production bases, and develop high value-added health products. Focus on health care products and daily chemical products such as Sanqi series, Dendrobium series and microalgae series, and build a number of brand products with sales income exceeding 1 billion yuan. Introduce well-known enterprises at home and abroad, cultivate some leading enterprises, and promote Yunnan’s health products to South Asia and Southeast Asia.

Construction of Yunnan laboratory for extracting characteristic plants. Focusing on plant extraction and scientific and technological innovation in the whole industrial chain of health products, we will systematically carry out basic research, product development and achievement transformation, and build a platform for functional evaluation and inspection of health foods and cosmetics. Using modern biotechnology, we will strengthen the research on the efficacy and application of animal and plant-derived ingredients, cultivate and expand a number of intensive processing backbone enterprises in the main raw material producing areas in view of the needs of food, medicine, health care products, daily chemical products, feed products and other related industries, and promote the extraction and processing of characteristic Chinese herbal medicines such as Panax notoginseng, Periplaneta americana and leech, as well as the raw materials of characteristic health products such as stevia rebaudiana, eucalyptus globulus, marigold, maca, rose, microalgae and aloe, and research and development. Improve the extraction and separation technology and quality level of panax notoginseng saponins, breviscapine, tea polyphenols, coenzyme Q10, paclitaxel, borneol and other extract products, as well as eucalyptus oil, citronella oil, rose oil, rosemary and other essence and fragrance products. Taking notoginseng, gastrodia elata, Dendrobium nobile, Polygonatum sibiricum, Amomum villosum and other medicinal and edible Chinese herbal medicines as raw materials, and special biological resources such as microalgae, Moringa oleifera, walnuts and flowers as raw materials, we have researched and developed various health products such as medicated diet, medicated wine, medicated tea and drinks, as well as a series of health foods, aromatic products and daily necessities with the functions of resisting oxidation, losing weight, enhancing immunity, relieving anxiety, relieving depression, assisting in improving memory and caring skin. Focus on developing and producing a batch of formula foods with strong pertinence and high patient acceptance, which are suitable for surgery, nephrology, oncology, pediatrics and geriatric rehabilitation.

Improve the development level of Panax notoginseng extract. In-depth study of extracts from different parts such as flowers, stems, leaves, roots, etc., and development of Sanqi series health food, special diet products, oral care, medical beauty skin care and other daily necessities in different dosage forms such as tablets, capsules and oral preparations, enriching product structure and expanding application fields; Improve the extraction technology and product quality level of panax notoginseng saponins, polysaccharides and panax notoginseng elements; Study and formulate international standards for the extraction of characteristic raw materials such as Panax notoginseng, and accelerate the internationalization of Panax notoginseng.

2. Rapid development areas

(1) Chemical drugs

Further improve the industrial chain, improve the research and development capabilities of original drugs and generic drugs, and improve the research and development level of high-end preparations.

Focus on Kunming, Chuxiong and other cities to build R&D and production bases for chemical drugs and chemical raw materials, and carry out R&D and industrialization of innovative drugs, improved new drugs, generic drugs and chemical raw materials.

Strengthen the joint development of "intermediates+APIs+chemicals". Improve the production technology of platinum anti-tumor raw materials and steroid hormone raw materials. Encourage enterprises to buy varieties with high clinical value at home and abroad and enterprises with great development potential to enter Yunnan for development. Develop chemical raw materials, auxiliary materials and packaging materials industries in areas with resources and environmental carrying capacity, and develop a number of chemical synthetic drugs with characteristics, potential and competitiveness. Strengthen exchanges and cooperation with Israel, India and other countries in the research and development of generic drugs, and explore the construction of an international cooperation base for the research and development of generic drugs.

Guide key enterprises and scientific research institutions to focus on the development of innovative drugs for major diseases such as malignant tumors, cardiovascular and cerebrovascular diseases, diabetes, mental diseases, viral infections, etc., especially chemical innovative drugs and improved new drugs with new targets and new mechanisms of action. Carry out research and development of high-end preparations, develop new dosage forms with good clinical substitution for varieties and dosage forms that are clinically necessary and have great side effects, and promote the research and development of sustained and controlled release, targeted, transdermal, mucosal and carrier drug delivery systems. Develop Yunnan plant resources, discover and develop new natural chemical drugs. To carry out the imitation of drugs needed for the treatment of major infectious diseases and rare diseases, drugs needed for the disposal of public health emergencies, drugs used by children, and original drugs whose patents are about to expire. Carry out research and development and green production technology innovation in the fields of chemical raw materials and pharmaceutical intermediates; Carry out the construction of the process technology system for the biosynthesis of important pharmaceutical monomer compounds such as panax notoginseng saponins and breviscapine.

(2) Medical devices

Give full play to the advantages of China (Yunnan) Pilot Free Trade Zone (hereinafter referred to as FTZ) and Border Economic Cooperation Zone, speed up the construction of medical device production and trade system for South Asia and Southeast Asia, develop high-tech and high value-added products, and establish an effective linkage mechanism between medical institutions and medical device industry.

We will build medical device industrial parks in Central Yunnan New District, Qujing, Yuxi, Free Trade Zone and Border Economic Cooperation Zone, build medical device R&D and production, inspection and testing, and trade distribution bases for South Asia and Southeast Asia markets, and build the most complete medical device industrial park in Southwest China.

In view of the market demand in South Asia and Southeast Asia, we will introduce domestic and foreign leading or advantageous enterprises in high-end medical devices and biomaterials to build medical device production bases and supporting industrial chains, cultivate high-end medical device enterprises, and promote the development of upstream and downstream industries of medical devices. Support the construction of a production base that meets the quality management standards for medical device production, build a public R&D and production platform for medical devices, build a high-grade medical device life-cycle detection technology service platform based on units with good foundation, and attract enterprises, research institutions, talent teams and technological achievements to Yunnan to carry out the transformation and industrialization of achievements. We will build a number of leading enterprises in the production of in vitro diagnostic reagents, dentures and disposable infusion devices, and promote the development of industries such as medical devices, new biomaterials, high-end pharmaceutical packaging materials and high-quality pharmaceutical excipients.

Develop technologies and products such as gene detection, biological detection chip and in vitro immunodiagnosis, and develop in vitro diagnostic equipment and reagents such as major emerging infectious diseases and tumor diseases; Accelerate the research and development of new biomaterials, and carry out research and development of new biomaterials such as biomedical materials, tissue engineering materials, bio-based materials and medical and health materials; Carry out research and development and production of high-end consumables such as orthopedic instruments, and build a production base of high-end orthopedic consumables in southwest China; Carry out research and development of TCM diagnosis and treatment instruments and equipment, rehabilitation instruments and equipment, and sports therapy equipment with ethnic characteristics; Carry out the development and industrialization of "big data+artificial intelligence+medical care" instruments and equipment, and develop digital and multifunctional mobile monitoring equipment and wearable products, rehabilitation AIDS and optometry-related products.

(3) Veterinary drugs

Further guide enterprises and scientific research institutions, strengthen investment in veterinary drug research and development, enhance the research and development ability of veterinary drugs, and give full play to the advantages of resources to develop innovative products of veterinary drugs.

Strengthen the cooperation between animal medicine enterprises and scientific research institutions inside and outside the province, and develop or introduce a new generation of animal vaccines and innovative products for veterinary medicine. Improve the quality and production capacity of a number of veterinary drugs, such as bovine O-type and A-type foot-and-mouth disease inactivated vaccine, pig O-type foot-and-mouth disease inactivated vaccine, pig double O-type foot-and-mouth disease inactivated vaccine, hog cholera live vaccine (subculture cell source), piglet paratyphoid, Newcastle disease and so on.

Focus on Kunming, Baoshan, Dali and other cities with veterinary drug industry base to actively develop veterinary drug industry. Increase the research and development of livestock and poultry disease prevention vaccines and pet vaccine products such as cattle, sheep, pigs and chickens; Develop a batch of veterinary traditional Chinese medicine preparations with traditional Chinese medicine as raw materials, which can replace antibiotics, carry out veterinary drug imitation research, develop feed drug additives, improve the self-sufficiency rate of veterinary drug production, and actively expand the market in South Asia and Southeast Asia.

(2) To improve quality and accelerate the construction of high-quality raw material bases for Chinese herbal medicines.

Highlight the construction of standardized planting (breeding) bases for Chinese medicinal materials, adhere to the principle of quality first, control the planting scale, innovate the planting mode, promote the original habitat planting, improve the quality of medicinal materials, and scientifically develop large varieties of raw materials such as Panax notoginseng, Erigeron breviscapus, Paris polyphylla, Gastrodia elata and Dendrobium. At the same time, give play to ecological advantages, actively introduce domestic and foreign high value-added medicinal varieties into Yunnan to build a high-quality raw material planting and processing base. Make good use of domestic and foreign resources and markets to build Yunnan into a national raw material base for high-quality natural medicines and health products.

1. Breeding excellent provenances and developing the fine variety industry of Chinese herbal medicines.

In order to promote the sustainable development of Chinese herbal medicine resources, the collection and evaluation of germplasm resources, screening of high-quality provenances, breeding of new varieties and breeding of improved varieties will be carried out around the backbone medicinal materials and rare and endangered Chinese herbal medicines, and the industry of improved varieties of Chinese herbal medicines will be developed. In view of the problems such as source degradation, we will strengthen the domestication and planting of Chinese herbal medicines and the breeding of improved varieties. Strengthen the investigation, collection, identification, preservation and artificial domestication and cultivation techniques of important rare and precious wild raw material germplasm resources such as Fritillaria cirrhosa, Euphorbia Humifusa, Rhizoma Curculiginis, Rhubarb and Dragon’s Blood, and protect the germplasm and genetic resources. In Wenshan, Zhaotong, Chuxiong, Dali, Lijiang, Pu ‘er, Baoshan and other authentic Chinese herbal medicine producing areas and suitable planting (breeding) areas, 50 breeding bases of authentic superior Chinese herbal medicines, 100 guaranteed nursery bases of Chinese herbal medicines and 100 standardized planting (breeding) bases will be upgraded, and a number of Chinese herbal medicine seed and seedling enterprises will be built, with emphasis on cultivating more than 10 high-quality seed and seedling management companies. Relying on the National Nature Reserve, conservation zone, a Chinese herbal medicine, will be built, and more than two protected areas for endangered and rare wild medicinal plants and animals will be planned, and more than 10 wild breeding bases for endangered and rare genuine medicinal materials from Yunnan will be built to provide support for the rapid development of raw materials industry for health products.

2. Strengthen the construction of high-quality raw material bases and build high-quality Chinese herbal medicine planting areas.

Build the "first workshop" of biomedical industry with the concept of green development. According to GAP standards, develop rural areas to revitalize the "one county, one industry" Chinese herbal medicine planting (breeding) industry. Innovate the planting (breeding) mode and vigorously develop "green planting", "ecological planting", "under forest planting" and "imitation of original habitat planting" of Chinese herbal medicines. Encourage domestic and foreign enterprises to build a "pharmaceutical park" in suitable areas of Yunnan, and accelerate the formation of a situation in which leading enterprises lead, bases are standardized and the province develops in an orderly manner. Cultivate a number of well-known enterprises and high-quality raw material varieties, and build a standard library of reference materials for Chinese herbal medicine varieties. Cooperate with neighboring countries to protect and organize traditional medicinal resources in South Asia and Southeast Asia, popularize planting techniques and carry out overseas planting. Strengthen the research and development and application of advanced equipment for planting Chinese herbal medicines, and improve the modernization level of planting (breeding) Chinese herbal medicines. Cultivate original bulk and regional comprehensive primary processing bases of Chinese herbal medicines, and lay out and build regional inspection and testing platforms.

Give full play to the advantages of Yunnan’s ecological environment, national culture and tourism industry, and promote the construction of a number of Chinese herbal medicine health industrial parks (manors) including standardized cultivation (breeding), food culture, health experience, leisure and health preservation, and popular science propaganda, with emphasis on building more than 10 well-known manors.

3. Accelerate the improvement and efficiency of "the hometown of Yunnan medicine" and build the brand of "Yunnan medicine"

Relying on the "Hometown of Yunyao", we will promote the construction of more than 60 standardized, large-scale and standardized planting (breeding) areas of high-quality Chinese herbal medicines, improve the standards of authentic Chinese herbal medicines, study and formulate a number of domestic and international standards for raw materials of health products, expand the scale of green planting and ecological planting of Chinese herbal medicines, standardize the whole process management of raw material planting (breeding), and build a quality monitoring network and traceability system covering the main producing areas of Chinese herbal medicines in the province. Build a green production technology promotion system, a production processing technology system, a quality evaluation system and a traceability system of the whole industry chain, and build a "Top Ten Yunyao" brand. We will carry out basic research on pharmacology, medicalization, efficacy and safety evaluation of Chinese herbal medicines, and develop a number of new food raw materials.

Build Sanqi into a national demonstration variety of Chinese herbal medicine intelligent agriculture. Improve the technology and level of green planting, undergrowth planting and original habitat planting of Panax notoginseng, and improve the supply capacity of high-quality and high-end products. Around the breeding, planting, processing, warehousing and other links of improved varieties of Panax notoginseng, we will build a comprehensive and domestic leading big data platform for intelligent agriculture of Panax notoginseng, and build a digital management and service system for seed and seedling quality evaluation, monitoring and early warning of pests and diseases, intelligent diagnosis, processing of origin, warehousing and logistics, quality inspection, product traceability and so on.

(three) to expand the market and accelerate the improvement of the business system of biomedical products.

Based in Yunnan, facing the whole country, South Asia, Southeast Asia and the Indian Ocean Rim, with the help of internet plus, big data, cloud computing and other modern technical means, we will give full play to the role of free trade zones and border economic cooperation zones, vigorously carry out internal and external cooperation, and build a business system for biomedical products with the focus on market system construction, enterprise management informationization and international business development.

1. Build a regional circulation system

Focusing on free trade zones and border ports, we will lay out and build a number of modern warehousing and logistics centers for biomedical products in all provinces, cities and key counties, cities, districts and border port cities such as Hekou and Ruili, build regional pharmaceutical wholesale and distribution centers, build cold chain logistics, and improve the supply guarantee system for pharmaceutical and health products in Yunnan. High-level construction of Yunnan Chinese herbal medicine trading center, enlarge and strengthen Wenshan Sanqi, Zhaotong Tianma and other regional characteristic Chinese herbal medicine markets, build a futures market for bulk medicinal materials and scarce medicinal materials, and cultivate a regional distributed trading market for fresh medicinal materials. Strengthen the supervision of Chinese herbal medicine market, standardize the access management of Chinese herbal medicine market, and establish a quality inspection, public warehousing and quality traceability system.

2. Promote the development of new logistics formats

Promote the "internet plus" business model, encourage drug circulation enterprises to use the Internet and Internet of Things technology, introduce third-party service organizations such as insurance and logistics, provide extended services such as online pharmacies and drug distribution, and build an information management system covering the whole province’s business circulation. Taking the Chamber of Commerce as the main body, we will jointly build the "Yunyao Information Network" and "Yunyao Database" to build the Yunnan pharmaceutical e-commerce trading platform. Develop the platform economy of "internet plus Traditional Chinese Medicine+Traditional Chinese Medicine+Health Service" and build a new format and new model economy of Chinese medicine industry.

3. Broaden the market channels of Yunyao.

Strengthen cooperation in commercial production, encourage commercial circulation enterprises inside and outside the province to sell Yunnan products, guide commercial circulation enterprises to build production and marketing alliances with raw material planting enterprises and pharmaceutical and health care products production enterprises, and provide market information and sales channels for production enterprises. Develop a number of specialized institutions that exchange and cooperate with domestic and foreign countries, and hold various seminars, exchanges and exhibitions. Encourage business circulation enterprises in the province to become bigger and stronger, and lead production enterprises, especially small and medium-sized enterprises, to expand domestic and foreign markets.

Fourth, the main measures

(1) Vigorously implement accurate investment promotion.

In-depth implementation of the "multiplication" plan of market players, focusing on biotechnology drugs, modern Chinese medicine, chemical pharmaceuticals, health products and other fields, aiming at the top 500 international companies, the top 100 biomedical companies and leading enterprises in the industry, and carrying out accurate investment promotion. Implement the drug marketing license holder system, and introduce innovative achievements holders such as biotechnology drugs, innovative Chinese medicines and chemical medicines to Yunnan to carry out achievements transformation and industrialization. Introduce and develop serum-free cell culture medium, affinity filler medium, ultrafiltration membrane, disposable reaction bag and other upstream and downstream supporting enterprises of biological products represented by vaccines to enter Yunnan for development. Introduce Chinese herbal pieces and health products processing enterprises represented by formula granules into Yunnan to build a raw material base, research and development production base and extend the industrial chain of Chinese herbal medicines. Implement the medical device holder system, give full play to the advantages of free trade zone and border economic cooperation zone, introduce medical device R&D and production enterprises to Yunnan, and build a medical device production and circulation base for South Asia and Southeast Asia. Introduce chemical raw material medicine enterprises into Yunnan for development in areas with resources and environmental carrying capacity. In combination with the introduction of science and technology into Yunnan, we will actively promote the "four landings" of talent teams, scientific and technological enterprises, scientific and technological achievements and innovation platforms, and strengthen the introduction of CRO (contract research and development institutions) and CMO (commissioned production institutions).

(2) Accelerate major projects.

Implement special projects for the development of biomedical industry, organize and implement a number of key projects to support and lead the development of biomedical industry. Relying on leading enterprises and R&D institutions with strong R&D capabilities, we will organize and plan a number of major projects combining "Industry-University-Research" for the development needs of key areas of biomedicine. With the goal of leading enterprises and key brand products becoming bigger and stronger, we will implement a number of quality improvement and efficiency improvement projects through digital and intelligent technological transformation and secondary development. With the goal of building industrial clusters, support key cities, key parks and key enterprises to plan and implement a number of key projects. Encourage the park to plan a number of preliminary projects and implement a number of key projects around infrastructure construction, key industrial bases construction and major scientific research platforms construction, and strengthen tracking management and service guarantee.

(C) focus on cultivating leading enterprises

Implement the cultivation plan of leading enterprises, and comprehensively improve the comprehensive competitiveness of pharmaceutical enterprises. In accordance with the principle of "one thing, one discussion, one enterprise, one policy", we will enlarge and strengthen leading enterprises, cultivate a number of large enterprise groups with international influence, develop and expand a number of key enterprises, support the development of small and medium-sized enterprises, and form enterprise clusters. In the fields of traditional Chinese medicine, biotechnology medicine, chemical medicine and health products, select a group of enterprises with good growth to focus on cultivation. Support enterprises to build raw material bases and production bases around the industrial chain, and improve the level of automation, intelligence and informatization of enterprises. Carry out the listing cultivation of biomedical enterprises, and continue to promote the listing progress of biomedical "golden seed" enterprises. Support enterprises to take capital, technology, brand as the link, through mergers and acquisitions, agreement transfer, joint restructuring, holding shares and other ways to carry out mergers and acquisitions, improve industrial concentration.

(4) Continuously improve the innovation capability.

Focusing on the fields of vaccines, antibody drugs, cell products, modern Chinese medicine, formula granules, chemical drugs, health products, extracts, etc., we will upgrade and build a number of industrial public service platforms and specialized research and development platforms, form a perfect biomedical research and development and technical service chain, and continuously improve the ability of biomedical innovation. Keep a close eye on the commanding heights of industry technology, increase investment in applied basic research, and reserve a number of advanced and applicable technologies and achievements; Adopt the innovative project organization mode of "unveiling the list", aim at the major needs of the industry, break through key technologies, formulate new standards, develop new products and upgrade new processes. With enterprises as the main body, we will build a number of R&D and service platforms such as key laboratories, technology innovation centers, engineering research centers, enterprise technology centers and industrial technology innovation platforms in conjunction with well-known expert teams and scientific research institutions at home and abroad. Promote the construction of the State Key Laboratory of Biomedicine for Non-human Primates, accelerate the construction of Yunnan Laboratory for Extraction of Characteristic Plants, build a new vaccine technology innovation system, and improve the research platforms such as natural drug screening, research on patent medicine, drug safety evaluation (GLP), drug pilot test, drug clinical evaluation platform (GCP) and bioequivalence test. Construction of provincial clinical medical research centers and a number of national clinical medical research sub-centers. Cultivate and introduce several CRO institutions. Promote and build a platform for big data and digital applications around the biomedical industry chain.

(5) Building professional parks with high quality.

With Kunming as the center and Yuxi, Chuxiong, Wenshan, Qujing, Baoshan, Honghe and other cities as the focus, a number of biomedical industry specialized parks covering the whole province will be built. Focus on promoting Kunming National Bio-industrial Base, Yunnan Central Traditional Chinese Medicine Natural Medicine Economic Circle, Yunnan Central Medical Device Industrial Park, Kunming and Yuxi Bio-vaccine R&D and production bases, International Medical Health City, Chuxiong Traditional Chinese Medicine Formula Granule Industrial Base, Wenshan High-tech Industrial Development Zone, Tengyao Industrial Park, Pu ‘er Biomedical Industrial Park, Honghe Biomedical Industrial Cluster, Qujing Malong Medical Device Emergency Industrial Park and other specialized parks and clusters. Based on the evaluation of the carrying capacity of resources and environment and the suitability of land and space development, chemical raw material medicine parks will be developed in Kunming, Chuxiong and other areas that meet the relevant policy requirements of chemical parks. Promote the gathering of projects, funds, talents and other elements in the park, strengthen the construction of public R&D and service platform, industrial incubation, infrastructure, industrial facilities and human resources conditions in the park, and form a regional specialized park integrating research and development, enterprise incubation, manufacturing and logistics distribution. Strengthen cooperation with biomedical industrial parks in Beijing-Tianjin-Hebei, Yangtze River Delta, Pearl River Delta and other regions, attract large domestic and foreign pharmaceutical enterprises, scientific research institutions and teams, CRO institutions and CMO institutions to settle in the parks, promote industrial agglomeration development, vigorously promote the construction of Kunming Great Health Industry Demonstration Zone, and build Kunming and Yuxi into important bases and agglomeration areas for modern biomedical production and research, and Chuxiong, Wenshan and other cities into important bases for modern Chinese medicine industry.

(6) Accelerate the training and introduction of talent teams

Adhere to the problem orientation, deploy the talent chain around the industrial chain and innovation chain, promote all kinds of talent training and introduction programs to the biomedical industry, further strengthen the training and introduction of high-level talents, and introduce high-end management talents, leading scientific research talents, high-level technical talents and innovative teams through multiple channels. Innovate training methods, train all kinds of talents, expand the enrollment scale of biomedical related majors in colleges and universities, and establish specialized talent training bases relying on qualified colleges and universities. Encourage social capital to set up vocational colleges and training institutions, promote school-enterprise cooperation, jointly cultivate and improve the quality of employees, and focus on cultivating a number of scientific and technological research and development talents, enterprise management talents, marketing talents, licensed pharmacists, quality management, testing and consulting service talents. Encourage the park to set up special funds for talents to provide more powerful talent support for the high-quality development of biomedical industry.

(7) Focus on building the brand of Yunyao.

Focus on the superior products such as vaccine series, Sanqi series and Dengzhanhua series, and build the brand of "Yunyao". To build a biological vaccine brand, we should build a specialized vaccine industry park, build a vaccine research and development system, develop innovative vaccine products, and promote the international development of vaccines. Extend the industrial chain of large varieties of Chinese herbal medicines such as Panax notoginseng, Erigeron breviscapus, Paris polyphylla, Dendrobium, Gastrodia elata, cultivate a number of large varieties of Chinese herbal medicines, and create geographical indication protection varieties. Develop ethnic resources of traditional Chinese medicine, develop and expand a number of dual-purpose varieties of traditional Chinese medicine, and promote the formation of a number of brand products such as Chinese herbal pieces, extracts, health foods and functional cosmetics. Implement the promotion action of famous Yunnan medicine products, give play to the leading role of the propaganda department, and form a publicity system with the participation of the government, enterprises and social organizations. Encourage enterprises to carry out various forms of publicity and promotion activities to publicize the advantages, characteristics, achievements, enterprises, brands, products and people of Yunnan’s development of biomedical industry. Build a brand display platform through various trade fairs such as South Expo and Drug Fair.

V. Guarantee conditions

(A) to strengthen organizational leadership

Improve the bio-pharmaceutical industry promotion mechanism, compact work responsibilities, hold regular meetings, analyze industrial development, study industrial policies, deploy promotion work, coordinate and solve key problems in the development of key enterprises and major projects, and promote vertical linkage at the provincial, prefecture and county levels. Further improve the horizontal linkage mechanism of provincial departments, enhance the joint efforts of all departments to promote the development of biomedical industry, and jointly create a good environment to promote the high-quality development of biomedical industry in Yunnan. An expert advisory committee on biomedical industry composed of senior experts in relevant fields inside and outside the province was established to provide strategic advice on the frontier situation, industrial analysis, innovation ability, regional layout, key investment promotion and policy design of Yunnan biomedical industry.

(2) Increase policy support.

Focusing on the research and innovation of new products, achievements transformation, market development and innovative service system construction in the fields of biotechnology drugs, modern Chinese medicine, chemical drugs, medical devices and health products, we will coordinate financial funds, increase investment and refine specific measures to support the innovation and development of biomedical industry. To obtain the national major new drug creation science and technology projects, the national key research and development plan related key projects, according to the law and regulations to give supporting support. Support for key core technology research and key new product development, comprehensive use of open competition, publicity system, horse racing system, directional selection and other ways to organize major innovation projects. Study and formulate policies and measures to support the development of biomedical industry in the free trade zone, and help Yunnan biomedical industry to go out and introduce. Incorporate key projects and major projects involving industrial development into relevant national development plans and strive for national policy support. Actively strive for the inclusion of superior and characteristic drugs in the national basic medical insurance drug list and the national basic drug list. Encourage all localities to adopt the form of "government subsidies, enterprises making profits and people buying" to promote the project of biological vaccines benefiting the people. Deepen the "streamline administration, delegate power, strengthen regulation and improve services" reform and promote the development of industrial agglomeration.

(3) Overall factor guarantee

Through scientific planning, revitalizing stocks, introducing increments and other ways, we will further expand the development space of biomedical industry, and encourage industrial parks to build standardized factories to meet the needs of biomedical R&D and production enterprises on the basis of meeting the requirements of land and space planning and environmental assessment at all levels. Overall balance of land use, electricity consumption, water consumption, sewage and other indicators, scientific planning and layout of biopharmaceutical and innovative drug production bases. Encourage the park in accordance with the principle of intensive land use, overall planning for the protection of the park urgently needed talent introduction, employment units or park employees accommodation construction land. Focus on advantageous fields and varieties, establish key enterprises and project libraries, give preferential policies to key projects, and streamline examination and approval procedures according to laws and regulations.

(D) Expand financing channels

Give full play to the role of provincial financial control group industrial investment fund, and guide key cities and parks to set up biomedical industry investment funds. Strengthen cooperation with various investment companies, banks and other financial institutions, and adopt various ways and mechanisms such as listing financing, equity investment, credit guarantee, risk compensation, bond financing and asset management to promote base construction, product development, achievement transformation and industrialization, enterprise cultivation, brand building and market expansion.

(5) Strengthening digital empowerment

Promote the digitalization of resources, digital industrialization and industrial digitalization in the biomedical field. Apply modern information technologies such as blockchain, big data and artificial intelligence to upgrade the construction of Yunnan biomedical industry big data center, and further improve the production, supply and marketing network of biomedical enterprises, Chinese herbal medicine bases and circulation enterprises covering the whole province. Promote the construction of Yunnan biological resources digital integration center to realize the sharing, trading and calculation of biological resources scientific data. Give play to the role of industrial big data platform, promote data sharing in R&D, production, approval, sales and use, and break down departmental data barriers.

(6) Pay attention to safety and security.

Strengthen the construction of biosafety risk prevention and control and governance system, strengthen the supervision and management of high-risk and medium-risk biotechnology research and development activities, and take effective countermeasures. Give full play to the role of Yunnan Science and Technology Ethics Committee, strengthen overall planning and guidance, strengthen scientific research ethics supervision, standardize all kinds of scientific research activities, strengthen safety training for managers and professional and technical personnel, and ensure the safe and healthy development of biotechnology. We will comprehensively promote the construction of drug safety regulations and standards system, highlight the improvement of supervision efficiency, enhance the ability of drug monitoring and evaluation, audit and inspection, inspection and testing, and intelligent supervision, and realize the mutual promotion of safety supervision and industrial development. Combine the construction of the vanguard of ecological civilization construction, implement the concept of green development, strengthen environmental protection during the development and application of biotechnology products, and ensure ecological security.

(7) Strengthen evaluation and supervision.

Establish a dynamic evaluation mechanism for the implementation of the plan, formulate a task list every year, and regularly supervise the implementation of the plan by the relevant departments of the state, city and province. We will build a supervision and service mechanism for the operation of key enterprises and the construction of major projects, strengthen the operation monitoring of key enterprises and the scheduling, tracking and service of key projects, and promote the early commencement, completion and commissioning of projects.

Attachment: 1. Atlas of Yunnan Biomedical Industry Chain

2. Regional distribution map of "hometown of Yunyao"

3 main indicators, main tasks and key work responsibilities.

Annex 1

Annex 2

Annex 3

Data Map of Liao Keduo, Political Commissar of Army in Eastern Theater

After the establishment of 13 newly adjusted group armies, the military battalion system was completely released. It is not only the reorganization of the organizational structure that is difficult for reform, but also the change of ideas, thinking and habits.

The "New Long March" can’t use the "old map"! Recently, Liao Keduo, the political commissar of the Army in the Eastern Theater, gave wonderful guidance on the implementation of the project to improve the ability of the brigade in the theoretical rotation training class for leading cadres in the Eastern Division. Among them, he broke five "stereotypes and bad habits", set up a new concept of keeping pace with the times, and directly attacked the ideological indulgence and conceptual shortcomings of the soldiers, calling on the officers and men in the Eastern Division to focus on fighting and promote the reform and strengthen the army.

These ice-breaking actions of thinking are like a long drought and showers, which makes officers and men unable to help but admire. Little friends can’t wait. Brother Frontline will take you to have a look.

★ Get rid of concept one

Don’t advocate regardless of what happened at home, and don’t recall cadres on vacation at will.

Regarding vacations, political commissar Liao’s words are simple, touching and warm to officers and men. He proposed that cadres and soldiers should be arranged to go back regardless of personal and family events such as officers and men, relatives dying in critical condition, family members having children, children taking the senior high school entrance examination and getting married, and so on. When officers and men are on vacation, unless there is a war or a major military action, they are not allowed to recall at will without special circumstances.

Do a good job and take a good vacation. Isn’t it better to put your heart and soul into your work after you have raised your spirit and adjusted your state?

However, once upon a time, it became a long-cherished and long-standing problem because of the needs of army building, management regulations and system requirements. Grassroots officers and men are looking forward to taking vacations, and they are even more afraid of being recalled in advance when they are on vacation; The leaders of the army have concerns and are embarrassed to take a vacation. It is not good to take the lead in taking a vacation.

It is necessary not only to be selfless, but also to pay attention to humanistic care, and to respect and safeguard the legitimate interests of officers and men. Political commissar Liao instructed that the "Notice on Issues Related to Visiting Relatives on Vacation for Servicemen" should be implemented. He said this: "Army leaders should take the lead in taking a vacation and set an example. Don’t feel that taking a vacation means that their mental state is not exciting, as if they have made some mistakes!"

Political commissar Liao doesn’t advocate ignoring what happened at home, but opposes promoting such cadres as typical ones. He praised the article "Do a good job and make a good wife" in the People’s Liberation Army Daily. He said: In fact, capable cadres should have successful careers, harmonious families and smart children.

Those comrades who have something to do at home and haven’t taken a vacation, let go of their ideological concerns, take a normal vacation and take a bold vacation!

★ Break the concept 2

Don’t let other standards "disturb" the fundamental and only standard of combat effectiveness.

Political commissar Liao said straight from the point that the standard of combat effectiveness is the only fundamental standard of the army. This should be said to be a common sense issue, which must be rigidly implemented and cannot be despised, squeezed or submerged.

But the ideal is full, and the action is skinny. In the past, it happened that even this common sense was "interfered" by some specious standards, such as safety standards, living standards, standards of being famous and registered, standards of being affirmed by superiors, standards of how many cadres were promoted, and so on, which led to the phenomenon of idling, turning in vain, wasting away and eating away, and gradually made the "steel rule" of combat effectiveness standards "soft".

The new concept advocated by Liao’s political commissar reminds us of the previous scenes: grasping the training order, stopping the equipment in a line, adjusting the gun barrel to a corner, shouting slogans in one tune, and training the movements in the same way, even pulling the box for combat readiness, all of them require to follow the queue; In the field training, the phenomenon of "camping" is even more "outrageous", and the officers and men are organized to wipe the ridges, lay stones and plant flags; When planning work tasks, the first thing that comes to mind is to achieve "several ones" and focus on how to write manuscripts, make boards and make films. These seem to have many achievements and highlights, but in essence many things deviate from the standard of combat effectiveness.

What makes people feel gratified is that a great wave of public opinion orientation, work orientation, employment orientation and policy orientation advocated by Liao’s political commissar focused on actual combat, which really hardened and consolidated the standard of combat effectiveness. In the past, old concepts and behaviors gradually drifted away in the Donglu army.

★ Break the concept three

The training ground resolutely abandons the negative safety concept of "paint on cars and skin on people"

Nothing is lost, nothing is lost.

"Safety goes wrong, everything is equal to zero".

Are you familiar with these slogans about the concept of security, troops leading troops? Political commissar Liao pointed directly at the crux of the problem. He stressed: to grasp actual combat training, we must vigorously correct the accumulated disadvantages of peace in preparing for war with a mentality of not fighting, change the negative safety concept of "cars don’t lose paint, people don’t lose skin" in the past, treat training accidents objectively, and guide all levels to really prepare for and practice training.

We used to have this phenomenon: we should have organized live-fire drills, but instead of being beautiful, safety first, we changed to indoor theoretical study; In order to prevent training accidents, high-risk courses and difficult training tasks are the "patents" of old drivers, and "novices" can only stand by as "spectators"; Some units had a little irresponsible accident, and all units stopped training …

Political commissar Liao pointed out that training is inherently a high-risk thing. It is impossible for a problem not to happen. The troops cannot stop to rectify when an accident occurs, and they must not artificially reduce the difficulty and risk for fear of an accident. This affects the construction of combat effectiveness. These phenomena that put security and stability from the bottom to the "first" position are the most intuitive manifestations of negative security at the expense of combat effectiveness.

As a "person in charge", you can’t let this sentence lack a "subject". The author understands that it is this positive security concept orientation established by the army in the eastern theater that rationally looks at the problems that occur in the training of troops, and truly "loosens the tie" for the brigade battalion chief and "unties the rope" for the improvement of combat effectiveness.

Well, did you get a shot in the arm?

★ Break the concept four

Don’t make rules outside the rules, don’t make rules outside the rules.

Grass-roots officers and soldiers understood the use of mobile phones and the driving of cadres. Political commissar Liao made these two things clear to everyone: the use of smart phones should not be blocked by layers, and the driving of cadres should not be simply banned.

In the past, the army often ridiculed that if "from top to bottom, layers of overweight, success at once", it would only bring "from bottom to top, layers of water injection, and it would be natural."

Although such a joke is somewhat exaggerated, it is not unreasonable. When some of our units implement the regulations of higher authorities, they are not original, but "adding materials" layer by layer, which leads to misery at the grassroots level.

Liao political commissar faced the problem directly and made the officers and men feel the same-

After the superior released the use of military smartphones, some still regarded smartphones as a "scourge", and did not handle what could be handled, and did not allow officers and men to use them normally, or even locked them in cabinets for centralized storage. Other smart functions have been blocked and become unintelligent "smart phones". The group that should master the means of informatization most can’t touch the products of informatization, which is caused by negative and conservative thoughts and incompatible with the requirements of the information age.

For the sake of safety, some units banned cadres from driving, which led to the friends mastering the skills of fighting, but losing the basic skills of daily life, which made many cadres feel embarrassed. Some cadres frankly said: when going home on vacation, either the wife drives or the old man drives, but the men at home can only stare blankly and worry.

Political commissar Liao also made it clear to us that cutting-edge things can be introduced into the army to better serve the army building and officers and men. What we can’t think of first is how to fortify, how to ban traffic jams, and how to block the door. We think less about positive effects and think more about negative effects, and we are struggling with advanced things, lacking confidence in leadership and management. We should stand in front of the times, face it bravely, strengthen education and guidance, do a good job in system standardization, pay attention to scientific management, and don’t let our policies become "fool" regulations and make cadres and soldiers feel uncomfortable.

★ Break the concept five

It is necessary to conduct downward pressure and prevent "micro-corruption" from having a market at the grassroots level.

At present, the anti-corruption work is in full swing. Grassroots officers and men support and praise the tigers that are far away from the horizon, but they hate the flies that are flying around in front of them, and they feel more directly about the micro-corruption that happens around them. It can be said that there are not many blood-sucking, and their harm is like tigers.

Political commissar Liao reminded everyone that it is necessary to put an end to "micro-corruption" at the grassroots level, beware of the phenomenon that "the beach is running out of water", and conduct pressure at all levels, from the beginning to the end.

Now, there is a new trend of "micro-corruption", which is worthy of vigilance. Have friends ever experienced such a pain: some accept WeChat red envelopes from subordinates, and some let people buy online goods without paying, and they are refurbished and infiltrated into the internet and sneaked into the ground.

In view of these problems, Liao’s political commissar has a clear-cut attitude, and "micro-corruption" is also a "great scourge". Grass-roots cadres should buckle their first button, be cautious, control themselves in private, resist temptation when no one is around, and guard the big festivals in detail, so as to make sure that they use their power in a well-regulated way, work in a colorful way, have affectionate and righteous exchanges, and live a well-regulated life. They should never go to places they shouldn’t go.

Political commissar Liao’s series of new ideas and concepts have completely broken the "pots and pans" of thinking on the way to reform and strengthen the army. Is it full of "earth smell" and full of positive energy, which makes your blood boil and make you hooked?

(The original title is "[Heavy] Liao Keduo, political commissar of the Eastern Theater Army, the new concept of" five breaks and five stands ",which won constant praise from officers and men")

Everyone has seen Xiaomi’s new car. Its name is YU7, which is one letter short of SU7. I was still a little confused about why I called this name. As a result, it was expected that the starting price of around 300,000 yuan would be smooth in an instant. It turned out that Xiaomi Yuqi was not aimed at Porsche this time, but at Tesla.

According to the available information, Xiaomi YU7 basically continues the style. The two cars are not exactly the same, but they are not bad. The front face with 99.99% similarity, from the front, is a fuller millet SU7. However, this is only limited to the front face. From the side to the tail, Xiaomi YU7 has gradually fine-tuned the details.

First of all, the most striking thing is the hub shape, which is changed from the original plum hub on Xiaomi SU7 to an ……emmm, which I personally think is really, really, really cheap. What can I say? It’s all right to call it hot wheels. If I choose a nickname, I can call it sports lottery hub directly. It doesn’t match the elegant texture of the whole car, just like Eddie Peng Yuyan’s figure. As a result, when I turned on the light, I found it was Song Xiaobao’s face. Of course, it’s just an analogy. The actual impact is not so great, but it means this.

Secondly, Xiaomi YU7 changed the straight air inlet hole at the fender of Xiaomi SU7 into a curved shape, and also adopted a hidden door handle shape with lower wind resistance and higher integration. Nothing to say, that is, reducing energy consumption and improving face value, praised. However, it should be noted that it is said that the hidden door handle of Xiaomi YU7 is not the mainstream automatic retractable door handle, but an inverted opening method similar to that of Toyota bZ3.

Finally, there is the tail that everyone cares about very much. Let’s not talk about Xiaomi SU7, just compare it with Ferrari, a "brother model". In fact, you will find that these two cars really have a lot in common. First, the design of hollow tail wing+inverted trapezoidal rear suspension window; Second, the rear fender is high and round, and it runs through the duck tail at the back; Third, the concave opening surrounded by the bottom; Therefore, in the end, an old saying was printed, that young people’s first millet YU7 should not be Ferrari Purosangue.

But let’s joke about it. Don’t really think that Xiaomi YU7 can really bring you the handling texture of Ferrari Purosangue. Obviously, from the first 45 angles of the two cars, the posture of Ferrari Purosangue will be much lower, so if everyone is controlling Xiaomi YU7, then it is recommended to put a correct attitude, not asking too much, just asking Xiaomi YU7 to be better and more fun than Model Y.

As for the interior of Xiaomi YU7, although there is no official information exposed now, I believe that everyone has not seen the spy photos exposed before. To sum up, family-style design, but with a remote screen. At present, the color matching that can be known will include "bone snail purple" and "red Dan orange" if there is no accident. And the configuration will be better than Model Y with a probability of 99.99%, including the next-generation Model Y that is still in the camouflage car stage.

So looking at the whole set, what do you think, brothers? Have you reached the standard in your heart? At present, Lei Jun himself revealed in Weibo that Xiaomi YU7 will not meet us so soon. If you want to buy it, you may have to wait until June or July in 2025 before it will be officially listed.

Anyway, I’ve thought about it. If I want to buy a car, the first thing I’ll do when I get it is to change my teeth for shock absorption, so that I can have Xiaomi and Purosangue at the same time.

　　"Dad, are you ready?" At the beginning of June, a series of copywriting appeared in an advertisement of a medical beauty client to warm up the newly launched "Double Eyelid Festival". This advertisement, which blew up the elevator, also caused widespread controversy because of the encouragement to young medical beauty practitioners implied by the word "Dad".

　　According to the analysis of the 2018 medical beauty industry white paper released by a medical beauty service platform, among every 100 medical beauty consumers in China, there are 19 "post-00", and the momentum of starting medical beauty consumption after 00 is stronger than that after 90. In 2019, the proportion of medical and beauty consumers under the age of 19 in China has reached 15.48%.

　　There are indications that the plastic surgery population is gradually becoming younger. Then, why did "after 00" choose cosmetic surgery early? What is the significance of plastic surgery for them? Is it necessary to have plastic surgery at a young age? Qianjiang evening news reporter conducted an investigation on this.

　　In plastic surgery, minors often appear accompanied by their parents.

　　Engaged in plastic surgery for four years, every winter and summer vacation, Liu Jun, a plastic surgeon in a 3A hospital in Hangzhou, will witness the peak of student gathering. "Almost every month, 60 or 70 students come for cosmetic surgery, accounting for 30%~40%."

　　"Most of them are high school graduates. Because they are about to enter the university, they hope to meet a new life and a new social circle with a better self." In recent years, the demand for medical beauty of high school graduates has been increasing year by year. Liu Jun understands their mentality, but from time to time he will meet several young medical beauticians who are at a loss.

　　"Campus Beauty" Trouble: Am I not very pretty?

　　The girl opposite talked about her various facial defects without thinking. But Liu Jun clearly saw that her face was white and beautiful, her skin was transparent and full, and her facial features were correct. He silently scored 95 points for the girl’s face value.

　　The girl’s name is Fangfang, 15 years old, and she is in Grade Three. She looks in the mirror frequently every day, makes "ugly" comments on herself distorted in her mind countless times, and consults medical beauty everywhere at any cost.

　　Finally, one summer, Fangfang, accompanied by her mother, sat in front of Liu Jun.

　　Liu Jun clearly saw that the girl’s eyes revealed a desire for change — — "My palate is leaning forward. Can I push it back?"

　　After entering the door, Fangfang’s mother just stood by without saying a word, smiling helplessly at Liu Jun.

　　"You are beautiful, there is no need to fix it." Liu Jun interrupted Fangfang’s words and directly denied her biased cognition of herself.

　　"You see, that’s what doctors say." At this time, the mother on the side spoke the first sentence, "I have been persuading for a long time before, but my daughter just doesn’t believe it."

　　In fact, because of her outstanding appearance, Fangfang, the "school flower", has always attracted much attention. But since entering junior high school, I heard someone say that another girl in other classes is more beautiful than herself. Fangfang has been dissatisfied with her appearance since then and started all kinds of strange behaviors.

　　"She is very demanding about her appearance and will constantly exaggerate her shortcomings. It is likely that there is a problem at the psychological level." After rejecting Fangfang’s plastic surgery idea, Liu Jun also made suggestions to the girl’s mother — — Pay attention to children’s psychological state.

　　A boy who visits the plastic surgery department once every three months

　　In the plastic surgery department where Liu Jun is located, Kobayashi, a boy under the age of 20, is also a frequent visitor. "Almost every quarter, he will come once, and the needs are different every time. In addition to me, many doctors also took care of him. "

　　Kobayashi is well-behaved, but he has been particularly concerned about his appearance since high school, and he can constantly find new defects. When he was still in high school, Kobayashi had a mandibular osteotomy in another hospital.

　　"Because of grinding, he has produced new dissatisfaction. Come to me for consultation six months after the operation. " Liu Jun said, "The boy’s mother also took great pains to greet me in advance alone, hoping that I would persuade her son."

　　Liu Jun successfully persuaded Xiaolin to go home, but half a year later, Xiaolin’s mother found the door again. "My son has been good for a while, but now he is entangled again."

　　Although Liu Jun repeatedly persuaded him not to have plastic surgery, Kobayashi always insisted on changing it, but he couldn’t tell the purpose and reason. "Because he paid too much attention to his appearance, he couldn’t concentrate on his studies. He only read until he graduated from high school." Liu Jun guessed that he might be psychologically hit by reasons such as lovelorn love. The best solution is not to find a plastic surgeon like Liu Jun..

　　"Go to the mental health department." In the face of young medical beauticians, Liu Jun often makes such suggestions.

　　Continue to write your own aesthetic mother on your children’s faces.

　　For cosmetic surgery, sometimes the young "post-00" will disagree with their families. "Some children really want to do it, and parents feel that it is unnecessary; There are also some children who have not yet formed aesthetics, but parents impose their own ideas on their children. "

　　"The child is still young, why do you want to cut her double eyelids?" Engaged in medical beauty for 28 years, Zhang Jufang, director of the medical beauty department of Hangzhou First People’s Hospital affiliated to Zhejiang University, met such a small patient for the first time — — Xiao Min, a 13-year-old junior high school girl.

　　"I think her eyes are not good-looking, and girls should have a pair of beautiful big eyes." Xiao Min’s mother said.

　　Zhang Jufang looked at Mandy sitting next to her. She listened to the conversation between adults with a puzzled expression on her face. Xiaomin knows nothing about plastic surgery. She only knows, "Mom asked me to do it, and I will do it."

　　After hearing Xiaomin’s answer, Zhang Jufang refused the operation. "The child didn’t ask for it herself. This operation is meaningless to her. Parents can’t make decisions for their children with their own aesthetics. " She told Xiaomin’s mother that she should decide whether to make facial adjustment after Xiaomin became an adult and formed her own aesthetic view.

　　Liu Jun also met a similar mother and daughter.

　　"As soon as I entered the door, the girl’s mother eagerly told me that her daughter’s eyes were ugly and her nose was ugly … … It doesn’t look good anywhere. "

　　Liu Jun remembers that it was an ordinary-looking high school girl who did have some defects, but the girl herself didn’t care about her appearance. "This mother’s mentality is a bit abnormal and she insists on plastic surgery for her children."

　　Plastic surgeons suggest:

　　Minors should not choose medical beauty.

　　Children’s psychology needs more attention.

　　"One of the most important tasks of plastic surgery clinics is to screen people and understand their plastic surgery purposes clearly." Liu Jun said with emotion, "Some children, we look normal, but they may be distorted in his eyes. In fact, this is a mental disorder and a kind of psychological paranoia. Plastic surgery can’t cure their mental illness. "

　　For young medical beauticians, double eyelid cutting and rhinoplasty are the most popular cosmetic items. According to the data released by a medical beauty service platform, "post-00" has quickly taken over from "post-90" and become a big consumer of medical beauty in double eyelid surgery.

　　Zhang Jufang also disagreed with the "66 Double Eyelid Festival" launched for the medical beauty service platform. "This is a marketing tool that sells double eyelids as products." Zhang Jufang said that double eyelids are an operation, not an assembly line product, and cannot be mass-produced. "It is not advisable to set a double eyelid festival, carry out large-scale promotion and encourage everyone to do double eyelids."

　　"Choosing medical beauty for younger people, from a clinical point of view, we are mainly based on two considerations." Zhang Jufang said, "Some children have congenital defects, such as cleft lip and palate. Performing cosmetic surgery for children can help him build confidence from an early age; Others are to make up for children’s psychological trauma and eliminate inferiority complex. For example, some girls have black hair moles on their faces and are teased by classmates. "

　　For young medical beauty practitioners, Liu Jun suggested, "We should wait until adulthood and establish a mature aesthetic view before considering this matter."

　　Zhang Jufang also believes that "minors should not choose medical beauty, and parents can’t ask their children for plastic surgery for their own needs. College students need to establish correct values and aesthetics, and they can pursue beauty, but not blindly. If you really want plastic surgery, you should also go to a regular hospital or medical beauty institution to communicate directly with doctors and listen to professional advice. "

　　(Except for Zhang Jufang, the characters in the text are all pseudonyms.)

　　　　　　　　 Qianjiang evening news reporter Rong Zhang Chen Xi

CCTV News:There are nearly 800 stations in Henan province with heavy rains of more than 100 mm, and the rainfall in Heping Mountain in Zhengzhou has exceeded the extreme value since the meteorological record. So why is this round of heavy rainfall in Henan so strong, and what is its cause? What’s the rainfall like today and tomorrow? What is the future direction and changing trend of rain belt? Let’s look at Zhu Dingzhen, chief meteorological service officer of the Public Meteorological Service Center of China Meteorological Administration.

Zhu Dingzhen, Chief Meteorological Service Officer of Public Meteorological Service Center of China Meteorological Administration:The cloud image of Fengyun-4 satellite on the morning of 21st shows that the convective cloud cluster is developing very vigorously, that is to say, the precipitation in the area under this cloud cluster is very intense. Judging from the whole rainfall, it has been concentrated in Henan area in recent days, which has caused a very large cumulative rainfall. Judging from the whole circulation situation, precipitation happened in the concave part of the massive subtropical high in Henan, which is what we often call the shear convergence area. The emergence of this convergence zone caused the southerly warm and humid air flow, including the easterly air flow, to converge over Henan. This will produce heavy precipitation, and the system moves slowly, so it will "stare" at the sky above this area. From the weather situation on the 17th to the 20th, we can see that the position has basically not changed much. This caused the precipitation to be strong and lasting for a long time, coupled with the influence of local topography, which stimulated and induced stronger precipitation.

On the 21st, there will be heavy precipitation at the junction of Hebei, Henan and Shanxi provinces, but the circulation situation has developed to some extent. Because the circulation situation moves with the typhoon, the subtropical high has an eastward trend, so the whole water vapor channel and wind flow direction will be different from the circulation in previous days. As a result, from the 22nd, the whole rain will be weakened.

　　CCTV News:Gao Fenglin, male, born in March 1962, Han nationality, party member of the Communist Party of China, is a special fusion welder and senior technician of Capital Aerospace Machinery Co., Ltd., the First Research Institute of China Aerospace Science and Technology Corporation.

　　Gao Fenglin has participated in a series of major aerospace projects, and the welded rocket engines account for nearly 40% of the total number of rocket engines. It has overcome the technical problems of Long March 5, and made outstanding contributions to the smooth implementation of national key projects such as Beidou navigation, Chang ‘e lunar exploration, manned space flight and the development of the new generation launch vehicle of Long March 5.

　　Honors won: second prize of national scientific and technological progress, national model worker, national May 1st Labor Medal, national moral model and most beautiful worker.

　　Gao Fenglin, male, born in 1962, Han nationality, party member of the Communist Party of China, is a special fusion welder and senior technician of Capital Aerospace Machinery Co., Ltd., the First Research Institute of China Aerospace Science and Technology Corporation. In his hands, the welding torch is a needle, and the arc light is a line. He pursues the welding light and welds a sky on the "golden thread" of the rocket engine. He is the special fusion welder of Capital Aerospace Machinery Co., Ltd., the First Research Institute of China Aerospace Science and Technology Corporation, the team leader of the rocket engine welding workshop, and the national senior technician — — Gao Fenglin.

　　It is said that Gao Fenglin is a "golden hand welding", not only because early people called the welder trained by argon gas, which is more expensive than gold, "golden hand"; It is also because the object he is welding is very expensive, and it is an engine known as the "heart" of the rocket; But also because he has reached a height that ordinary people can’t reach in the field of rocket engine welding. "Golden Hand and Sky Welding" is a portrayal of Gao Fenglin’s superb skills and repeated difficulties in welding technology, and it is also the embodiment of the elegant demeanor of high-skilled aerospace workers in the new era.

　　First, I am determined to serve the country and practice welding skills in the aerospace industry.

　　Gao Fenglin, who just stepped out of school, entered the argon arc welding group of the rocket engine welding workshop with abundant talents, and studied skills with the first generation of argon arc welders in China. In order to practice basic skills, he used to use chopsticks to gesture welding and wire feeding when eating, used to hold a jar full of water to practice stability when drinking water, held an iron block to practice endurance when resting, and even braved the high temperature to observe the flow law of molten iron. Gradually, Gao Fenglin’s accumulated energy generate came out.

　　In the 1990s, the welding of the large nozzle of a new type of high thrust hydrogen-oxygen engine designed for China’s main rocket Changsanjia series launch vehicles once became a bottleneck in development. The length of all welds is nearly 900 meters, and the pipe wall is thinner than a piece of paper. If the welding torch stays for 0.1 second, the pipe may burn through or leak. Once burn through and leak occur, not only the large nozzle will be scrapped, but also the development progress and launch date of the rocket will be affected. Through continuous exploration, Gao Fenglin and his colleagues overcame two major difficulties, namely burning through and welding leakage, with superb skills. However, the X-ray inspection of the first welded large nozzle shows that there are more than 200 cracks in the weld, and the large nozzle will be sentenced to death. Undaunted, Gao Fenglin made an analysis and investigation from the aspects of material performance and structural characteristics of large nozzle. In the end, at the high-level technical analysis meeting, he boldly said in the questioning voice of many technical experts that it was a fake crack! After the cutting test, it is shown that his judgment is correct under the microscope of 200 times. In this regard, the first large nozzle was successfully sent to the test bench, and the successful application of this new type of large thrust engine greatly improved the carrying capacity of our rocket.

　　With more and more urgent and difficult jobs, Gao Fenglin has shouldered more and more burdens. In the welding research of a certain type of ejector, he made bold improvements, which solved the unsolved problems in the past year and a half and ensured the delivery of products with an output value of nearly 100 million. The launch system of a national submarine-based key model is in trouble near the critical moment of launch. Under the direct instruction of the model chief engineer, Gao Fenglin studied and adopted special techniques, and eliminated the fault overnight, thus ensuring the launch of this product as scheduled.

　　Second, the courage to innovate, self-breakthrough achievement expert workers

　　Gao Fenglin dared to try in his work, persisted in innovation and breakthrough, and turned countless "impossible" into "possible". The qualified rate of a certain engine component is only 35%. It takes half a year for the model to produce a large number of qualified products. This product is processed by soldering, while Gao Fenglin’s major is fusion welding, which is a cross-disciplinary research. Gao Fenglin understood the mechanism from the theoretical level and grasped the key from the technical level. He ran to the library, browsed professional and technical websites, and tried his best to search for relevant information at home and abroad. Every day, Gao Fenglin led the team members to conduct experiments in an operation room of more than 20 square meters, and conducted hundreds of experiments in two months, clarifying the genetic mechanism of the two materials, and repeatedly improving them from the aspects of environment, temperature and operation control. The final processing technology made the qualified rate of the product reach 90%.

　　The continuous success did not make Gao Fenglin feel high. Instead, he felt the value of knowledge more and more, and thought that operators should arm their minds with wisdom to better guide the practical operation. After leaving school for 8 years, Gao Fenglin re-entered the campus, picked up his textbooks and began his hard spare-time study for 4 years. During the day, he shuttled to the work site, training ground and classroom, and at night, he studied with two thick stacks of books until 3 or 4 o’clock. Due to excessive tension and fatigue, his hair fell off in handfuls when he was less than 30 years old. Everything comes to him who waits. Gao Fenglin first achieved good results in practice and theory in the technical competition, and soon got a college diploma that he had been looking forward to for many years. After that, he completed his study from undergraduate to graduate.

　　Not only can you do it, but you can also write it to guide others to do it. Gao Fenglin has been asking herself this way. In the butt welding of engine nozzle, which is very difficult to operate, Gao Fenglin studied the characteristics of the product and applied what he learned flexibly, and put forward the "anti-deformation compensation method" to control the deformation. Later, this process won the second prize of national scientific and technological progress; He also edited the first model engine welding technical operation manual and other industry specifications, and was appointed to participate in the formulation of relevant aerospace standards for many times. Through the process of self-study, practice, summary and re-practice, Gao Fenglin has gradually become an authoritative welding expert in China and an expert worker who combines profound theory with exquisite skills in everyone’s eyes.

　　In 2006, the antimatter detector project involving 16 countries and regions in the world was in trouble because of the manufacturing problem of low temperature superconducting magnets. The proposals put forward by two groups of international and domestic technical experts failed to pass the review of the international alliance led by the National Aeronautics and Space Administration (NASA). At a loss, Professor Ding Zhaozhong, a Nobel Prize winner, inquired about Gao Fenglin and asked him to help. Gao Fenglin went to the site to conduct basic research and textual research. He pointed out: according to the traditional control method, the previous two schemes are impeccable, but there are great hidden dangers for this special structure. He stated his design scheme, which was finally recognized by NASA and the League of Nations. An expert commented on Gao Fenglin: "You have both profound theory and rich practical experience. You look at the problem from two dimensions. It seems that highly skilled talents are of great use!"

　　Third, be willing to give, and work hard to witness the ordinary greatness.

　　The particularity and risk of aerospace products determine that many problems must be solved under very difficult and dangerous conditions. Gao Fenglin is willing to devote himself to the front line of welding, working hard, facing up to difficulties at the most needed moment, and has made extraordinary achievements in his "ordinary" post.

　　In order to meet the launch of large-capacity and large-tonnage satellites, China has built the largest full-arrow vibration test tower in Asia, in which the welding of the vibration girder is the key, which belongs to the first-class weld, and the material used to make the vibration girder is very special and the welding is very difficult. In order to meet the welding requirements of vibrating girder, Gao Fenglin should operate continuously at high temperature. The surface temperature of the weldment reached several hundred degrees, and Gao Fenglin’s hands were baked dry, and a series of blisters were bulging. In order to finish the task on time and with good quality, he gritted his teeth and finally welded a qualified vibration beam. During the later manned spaceflight project, the vibrating girder was upgraded and tested. The results show that the welding quality of the girder is good, and the bearing capacity can be increased from 360 tons to 420 tons, which can continue to serve for the development of launch vehicles in China. The vibrating girder has stood the test of time, and Gao Fenglin’s hands are still scarred by severe burns.

　　During the development and production of Long March 5, the engine suddenly leaked from the inner wall during the launch pad test. Standing on the test bench facing the product, behind him is a mountain stream of tens of meters, and Gao Fenglin is fearless in times of crisis. Because of the special environment, the fault point can’t be observed, and the operating space is very narrow, Gao Fenglin managed to finish the "emergency rescue" by using superb skills and special techniques under the condition that he could barely fit into one arm.

　　Gao Fenglin has been rooted in the front line of aerospace and engaged in the welding of rocket engines. He has overcome more than 200 difficulties in major research projects of aerospace product engine models. He has also actively contributed his talents to fill technical gaps in titanium alloy bicycles, large vacuum furnaces, ultra-thin large bellows and other fields, creating value for the national economy. Foreign-funded enterprises have been hired with high salary and housing, and he is unmoved; Many times can be promoted, Gao Fenglin also gave up. He always believed that his roots were in the welding post.

　　Fourth, willing to educate people, preaching and teaching paved the way for peaches and plums.

　　It is not spring to outshine others. Apart from being a master of skills, Gao Fenglin also has a significant job, which is to continuously train more outstanding aerospace high-skilled talents like him.

　　In terms of technology inheritance, Gao Fenglin unreservedly passed on his accumulated rich experience to young people. He groped and summed up a set of methods for talent training and management. His advocacy of "mentoring by teachers" and "One Belt and One Belt" and his creation of "welding" education method have been widely recognized and applied in practice. It has cultivated five national technical experts and one central enterprise technical expert. He was invited by the Central Organization Department and Publicity Department of the Communist Party of China to have an exchange of "artisan spirit", participated in the "activities of artisans from big countries entering the campus" and "exhibition of innovative achievements of workers on both sides of the Taiwan Strait" of the All-China Federation of Trade Unions, and actively promoted the spirit of model workers, labor spirit and craftsman spirit.

　　In 2005, Gao Fenglin’s team was jointly named "Gao Fenglin Team" by China National Defense Posts and Telecommunications Union and Aerospace Science and Technology Corporation, becoming the first team named after a model worker in the First Aerospace Institute. As a demonstration base for team building, Gao Fenglin team has fully played a typical demonstration and radiation-driven role in producing models, achievements, talents and experiences. Teams and teams have teamed up with more than 30 teams inside and outside the space system to carry out various exchanges and cooperation. Through technical cooperation, more than 20 major scientific research topics such as aerospace engine welding and development have been solved. Received many training courses for national excellent team leaders of the Ministry of Human Resources and Social Security, as well as visits and exchanges from nearly 200 brother units such as China Commercial Aircraft, China Electric Power Branch and Shougang Group. Under the leadership of Gao Fenglin, the team has successively won many honorary titles such as "National Worker Pioneer", National Learning Excellent Team, National Safety Production Demonstration Team and Central State-owned Enterprise Learning Red Flag Team "Benchmark" with its impressive performance. In 2011, Ministry of Human Resources and Social Security awarded Team Gao Fenglin as a national skill master studio. In 2017, the All-China Federation of Trade Unions awarded Gao Fenglin Team as a national model model worker and craftsman talent innovation studio.

　　At the moment when the ambulance siren sounded, in addition to the patients and their families waiting anxiously, there were also emergency medical staff who were eager to get to the scene. In the face of patients seeking help, ambulance drivers play a vital role in fighting for rescue time. In recent days, drivers in the emergency department of Jinshui District General Hospital in Zhengzhou City have become "on fire". In order to shorten the visiting time, more than a dozen drivers spent nearly half a year in their spare time to draw a visiting map covering 1,056 residential buildings in 52 communities. A few days ago, Beijing Youth Daily reporter learned from Director Zhao of the emergency department of Jinshui District General Hospital in Zhengzhou that the use of the visiting map shortened the visiting time by 5 to 10 minutes, and it will be continuously updated and improved according to the construction of residential areas within the visiting scope in the future.

　　45 hand-painted maps bring together 1056 buildings.

　　Recently, the hand-painted map of the driver’s class in the emergency department of Jinshui District General Hospital in Zhengzhou City was "on fire", especially in the emergency circle in Zhengzhou City, the provincial capital, and many people consulted "learning from the scriptures".

　　A few days ago, the reporter of Beiqing Daily contacted Director Zhao, the emergency department of the hospital. According to him, this map of visits began to be planned very early.

　　At the beginning of 2016, after Jinshui District General Hospital moved to its current new location, there were many large-scale residential areas in the core visiting area of the emergency department, and the situation of the residential areas was also complicated, many of which were special. "For example, there are 14 small courtyards irregularly distributed in a large-scale community, and each small courtyard is independent of each other and has different access controls." Director Zhao said that it is sometimes difficult for medical staff who often receive patients to find the building where the patients are located during the day, and it is even more difficult to find the road at night. "Later, we thought, can we mark the roads in each community for the convenience of all drivers?" Later, more and more communities needed to be marked, and everyone simply collected the details of more than 50 communities.

　　Shi Shuai, the driver of the emergency department, once studied painting. He was mainly responsible for sketching in the process of making the map of home visits, and the rest of the drivers were responsible for on-site exploration of the roads and entrances of the community and marking them in detail on the map.

　　It starts from Lianhuo Expressway in the north, the North Third Ring Road in the south, Jinbei Road in the west and Wenhua Road in the east. In the core visiting area of Jinshui District General Hospital in Zhengzhou City, the masters of the driver class spent half a year familiarizing themselves with the specific conditions of more than 50 residential areas, and then they were drawn on 45 hand-drawn residential area plans by Shi Shuai, the driver and first aid worker.

　　The average consultation time is shortened by 5 to 10 minutes.

　　"The traffic conditions of roads in the community, including traffic lanes and pedestrian walkways, as well as the traffic conditions of each door in the community, especially those with fire doors and fire exits, are often the most convenient first-aid passages." Shi Shuai said that in addition to marking the location number of each building in the community, it is also necessary to clearly mark the orientation position of each unit. "Especially in the case of poor sight at night, it is convenient for medical staff to quickly find the patient’s home."

　　The reporter of Beiqing Daily noticed that the contact information of the property was still left on the floor plan of many communities. Shi Shuai explained that in some high-end residential areas, it is difficult for ambulances to enter because of the separation of people and vehicles and the low underground garage door. "Everyone wrote down the switchboard of the property according to their experience. Once you receive the mission of visiting critically ill patients in the community, call the property switchboard at the first time, ask the security guard to open the ground fire door in advance, and lead the ambulance to the corresponding building to treat the patients in the most timely manner. "

　　The drawing of the home visit map directly shortens the time of receiving treatment in the emergency department. What impressed Shi Shuai was that at the end of 2017, he and his colleagues had just finished drawing the area of nearby Provence Community, and the emergency department received a call for help. Ms. Liu of Provence VI had a heart attack, and after calling 120 for help, the medical visiting team quickly determined the location according to the "visiting map". With the cooperation of the property personnel, Ms. Liu was quickly found and sent to the hospital, and finally Ms. Liu was successfully rescued.

　　"Now the 45 maps we have drawn basically cover all the reception areas of the hospital. Once we receive a phone call to confirm the location, we will find the corresponding location on the map and soon find the best way to get through. The reception time is shortened by 5 to 10 minutes on average." Shi Shuai introduced.

　　The map specially marks the location of special people.

　　In addition, Shi Shuai said that he and his colleagues also specially marked the location of special people in the community on the map. "For example, there are many elderly residents in some communities. The buildings No.19 and No.20 in a certain community are low-rent houses, and all of them live in low-income households, even the disabled and widowed elderly. In response to their help, our doctors, nurses and drivers must try their best to give special care. "

　　Master Xia worked in the emergency department of Jinshui District General Hospital for many years. Once he received a 120 call for help, he learned that an old man in his 90 s suddenly became incontinent, and his son in his 70 s took care of the old man. Because the elevator is too small, it can only be carried by people. "Master Xia picked up the old man without saying anything and sent him to the ambulance." Shi Shuai said that no matter which driver in the driver’s class encounters such a situation, he will fight for more rescue time for the patient like Master Xia.

　　Talking about the original intention of hand-painted maps, Shi Shuai said that in fact, the original intention of hand-painted maps is to compress time against time and get patients treated as soon as possible. "As long as you work in the emergency department for one day, everyone can feel that time is life."

　　"After our hand-drawn map is made, the driver class will have one copy, which greatly improves the efficiency of home visits." Director Zhao said that because of the rapid construction of Zhengzhou North District, this hand-drawn map will be further improved with the surrounding environment and the construction of residential areas.

　　Text/reporter Zhang Xiangmei

() The business review of the Board of Directors in 2021 is as follows:

　　I. The industry in which the company is located during the reporting period.

　　The company shall comply with the disclosure requirements of "Software and Information Technology Service Industry" in the Guidelines for Self-regulation of Listed Companies of Shenzhen Stock Exchange No.3-Disclosure of Industry Information.

　　1. China will accelerate the development of digitalization and create new advantages of digital economy.

　　From a macro perspective, the Outline of the Fourteenth Five-Year Plan and the Long-term Goals in 2035 proposes to meet the digital age, activate the potential of data elements, promote the construction of a network power, accelerate the construction of a digital economy, a digital society and a digital government, and drive the changes in production methods, lifestyles and governance methods with digital transformation as a whole. Promote digital industrialization and industrial digitalization, promote the deep integration of digital economy and real economy, and build a digital industrial cluster with international competitiveness. Under the wave of digital economy, as the main body of the digital economy era, the digital transformation of enterprises is the only way. At the specific enterprise level, enterprises should accelerate the breakthrough of 5G, big data analysis, artificial intelligence and other technologies around practical application scenarios, build a safe and controllable digital transformation technology system, and make changes in digital talent training and government policy support. Premier Li Keqiang gave clear instructions in the Report on the Work of the State Council Government in 2021 to "accelerate the development of digitalization, promote the digital industrialization and industrial digital transformation, and improve the level of digital government construction". The company will seize the opportunity and use its own advantages to help customers in various industries digitally transform.

　　2. Industrial Internet

　　Industrial Internet has become the competitive focus of a new round of global technology and industrial revolution. The State Council, the CPC Central Committee, attaches great importance to the integration and development of next-generation information technologies such as Internet, big data and artificial intelligence with the real economy. In January 2021, the Ministry of Industry and Information Technology issued the Action Plan for Innovation and Development of Industrial Internet (2021-2023), which laid out the key work contents of industrial Internet in the next three years, representing that China’s industrial Internet industry has entered a new stage at a new height and started a new journey. According to GE’s forecast, the industrial Internet will affect 46% (about 32.3 trillion US dollars) of the global economy, and by 2030, the industrial Internet will bring about 15.3 trillion US dollars of GDP growth in the world, and at least about 3 trillion US dollars of GDP growth in China. According to the concept of 1% industry value-added put forward by Academician Wu Hequan, the leader of the State Council Internet of Things Leading Group, it is estimated that the early industrial Internet market space can bring 1% value-added to this industry, which means opening trillion market space. 5G is the starting point of the transformation from consumer Internet to industrial Internet, and industrial Internet is the most anticipated application field of 5G. 5G drives the development of industrial Internet, which accelerates the deployment of 5G commercial scale, and the integration of 5G and industrial Internet has a significant multiplier effect. Miao Wei, Minister of the Ministry of Industry and Information Technology, once pointed out that 5G applications will be distributed in a "two-eighth law", and 80% will be used in the industrial Internet. The enthusiasm of China’s industry to promote the integration and innovation of 5G and industrial Internet is constantly improving, "5G+ industrial Internet"Intranet construction and transformation covers a wide range of industries, and its application scope continues to extend to the core links of manufacturing, and the superposition multiplication effect and huge application potential are constantly released.

　　3. Big data, cloud computing and artificial intelligence

　　Focusing on the development of digital economy, the Outline of the Tenth Five-Year Plan and Long-term Goals in 2035 further defines the development of seven key industries, such as cloud computing, big data, Internet of Things and industrial Internet. In 2025, the added value of core industries of digital economy will account for 10% of GDP. The word "big data" appeared 14 times in the draft of the planning, while the word "data" appeared more than 60 times. The new generation of information technology driven by big data is changing from "cutting-edge technology" to "important application", and its value is becoming more and more obvious. The provision form of big data technology has evolved from "product-oriented" to "service-oriented" five years ago. Solutions that provide a variety of underlying technologies and provide convenient services in all aspects of development and operation are increasingly becoming the mainstream choice for the big data supply side. As the main resource carried on the information infrastructure, data is the "blood" of the new infrastructure. Network, Internet of Things and data center are important infrastructures for the development of big data, and the development and construction of supercomputing center, industrial Internet and vehicle networking are also inseparable from the analysis and processing of data. The white paper on cloud computing development of China Information and Communication Research Institute shows that the scale of China’s cloud computing market will be about 178.1 billion yuan in 2020, and it will maintain rapid growth in the next few years. By 2025, the market scale will exceed 700 billion yuan. In the digital transformation of industry, digital infrastructure is the production tool and data is the means of production. Taking cloud computing as the core and integrating artificial intelligence, big data and other technologies can realize the transformation and upgrading of enterprise information technology software and hardware.Innovate application development and deployment tools, accelerate data circulation, collection, processing and value mining, and effectively improve application productivity.

　　4, the innovation industry accelerated.

　　Innovation is information technology application innovation (), which is the foundation of data security and network security, and also an important part of new infrastructure. For a long time, China’s dependence on non-domestic IT products is high, and the discourse power of the underlying architecture standards and the upper ecological construction is weak, which leads to a relatively passive situation. Xinchuang is a long-term solution for independent innovation, development and upgrading of China’s IT industry. On January 12, 2022, the "14 th Five-Year Plan" for Digital Economy Development was released. Among them, independent technology, infrastructure, industrial digitalization and digital industrialization, data security and governance are the core contents. The "Planning" points out that it is necessary to aim at important technical fields such as industrial software, high-end chips and operating systems, give play to the advantages of the new national system and the ultra-large-scale market, and fill in the shortcomings of key technologies. According to the data of "China Xinchuang Ecology in 2021" published by Haibi Research Institute, the actual scale of China Xinchuang ecological market is 161.7 billion yuan in 2020, and it is predicted that it will maintain rapid growth in the next five years, with a compound annual growth rate of 37.4%, and it will reach 800 billion yuan in 2025. With the successful demonstration in the field of party and government, Xinchuang industry has accelerated to eight key industries such as finance, telecommunications, energy, electric power, medical care, education, transportation and public utilities. Dongfang Guoxin has always insisted on independent research and development and innovation. At present, it has formed an independent and controllable technology and products in the whole industry chain, and will actively participate in the national innovation industry in the future.

　　5. "East Counting and West Counting" has been upgraded to the national strategic level.

　　As the base of digital economy, computing power is highly valued by the country. As an important starting point for new infrastructure to affect China’s macroeconomic development, and a major project to realize the "digital network" system in the national integrated big data center collaborative innovation system, big data centers will create a new engine for the development of digital economy. It shows that the country attaches great importance to digital construction. The strategic positioning of "counting from the east to the west" can be used to benchmark national projects such as "South-to-North Water Transfer Project" and "West-to-East Power Transmission Project", and the annual investment volume will reach several hundred billion yuan. The data center has a long industrial chain, large investment scale and strong driving effect. Through the construction of computing hub and data center cluster, the upstream and downstream investment of the industry will be strongly promoted, and the pulling effect on related industries will reach 1: 8. According to the deputy director of the Innovation-Driven Development Center of the National Development and Reform Commission, "East Counting and West Counting" can drive social investment to exceed 400 billion yuan every year, which is significantly higher than the new infrastructure policy in 2019 and 2020.

　　

　　II. Main businesses of the Company during the reporting period

　　(I) Introduction of the company’s main business

　　The company’s main business is to provide customers with enterprise-level big data, cloud computing, industrial Internet and other platforms, products, services and overall industry solutions. In terms of technical products, based on cutting-edge technologies such as big data, cloud computing, artificial intelligence, industrial Internet, 5G and machine learning, it provides related technical products including data collection, data storage and calculation, data analysis and mining, data application, data governance and control, cloud basic services and application development platforms; In terms of industry solutions, based on the company’s many years of business experience, we provide solutions and technical services to customers in communication, finance, industry, government and public safety industries, helping customers to form high-quality data assets, explore the deep-seated value of data, and improve the utilization rate of IT resources and service capabilities, so as to obtain higher production efficiency and operational benefits and help enterprises to digitally transform.

　　(1) product line of database and big data open source system

　　Dongfang Guoxin has developed big data technology products with completely independent intellectual property rights, which are safe and controllable, covering CirroData high-performance distributed database, enterprise-level big data platform BEH, B-SCOP service capability open platform, real-time computing decision engine product B-RCDE, real-time transaction data acquisition product B-RTDA, B-Spider data collector and other products. These products have been widely and successfully applied in many industries.

　　(2) Industrial Internet product line

　　Cloudiip, the industrial Internet platform of Dongfang Guoxin, is completely independently developed and built by Dongfang Guoxin. While providing in-depth services to industries such as ironmaking, heating, electric power, energy, rail transit, automobile and machinery manufacturing, it also optimizes equipment management, R&D design, operation management, production execution, product life cycle management and supply chain collaboration for industrial fields such as asset management and energy management, and important equipment such as air compressors and industrial boilers, forming a platform covering R&D, production, management and service fields.

　　(3) Public cloud product line

　　Oriental Guoxin Cloud BONCLOUD is a cloud service platform based on the company’s advanced cloud computing technology and rich software products for many years, combined with high-quality data center resources, and on the basis of in-depth understanding of the business needs of the government, operators, the Internet and traditional enterprises in different scenarios. The platform provides safe and stable cloud computing resources such as flexible computing, storage, network and CDN.

　　(4) Data science and artificial intelligence product line

　　Facing the market demand, Dongfang Guoxin integrates products and technologies such as BI construction, interactive exploration, SPSS, artificial intelligence and deep learning, and develops 2B and 2C products based on the cloud platform architecture.

　　1 Turing Turbo Engine: This is a one-stop artificial intelligence platform and a complete enterprise-level AI solution for data scientists, data engineers and business analysts. The product is rich in SPSS native high-quality algorithms, integrating data connection, data exploration, feature engineering, algorithm implementation, model development, model release and management, providing a collaborative project space for teams and individuals, greatly improving work efficiency and helping enterprises to quickly realize the integration of AI and business.

　　② Turing Topia of Turing Federation: Turing Federation (turingtopia.com) is a data science community platform built by Dongfang Guoxin, which integrates competitions, data sets and models, and brings together various resources, tools, data and data engineers. In addition to the competition community, the company’s products include Turing Training, Turing Crowdsourcing, Turing Lab and Turing Cloud.

　　(5) Data tools and data application product lines

　　① Data governance platform BDG: Help customers to establish enterprise-level data centers, carry out big data governance from top to bottom, integrate enterprise data by using the basic capabilities provided by the data governance platform, realize unified control and refined management of data, and ensure the quality of data assets. Support () application, promote enterprise big data analysis, tap the potential value of data, and provide strong support for enterprise strategic decision-making, business system, risk management and control, etc.

　　② Data Cloud: Data Cloud can help enterprises to get rid of the dilemma of high overhead and low output of traditional system architecture in big data environment. By building an integrated platform for data production and service, the data supply system is reconstructed, and business innovation is driven by data to achieve cost reduction and efficiency improvement.

　　③ Marketing Cloud: The marketing cloud is positioned to build a one-stop intelligent marketing management cloud platform that integrates omni-channel resources and is digitally driven, and realize the closed-loop process of intelligent marketing from customer insight, activity planning, marketing strategy matching, activity execution and effect evaluation. Help enterprises recommend the right products to target users in the right channels and at the right time, realize the data-driven target marketing model, and make marketing efficient, intelligent, simple and accurate.

　　④ Excellent Cloud: Integrating multi-domain data and relying on big data applications to provide managers with accurate and real-time human resources allocation and management around the strategic transformation of enterprises and the promotion of human resources value; Provide comprehensive, timely and personalized services for employees; It provides decision-making basis and means for the work of "breeding and keeping".

　　⑤ Data visualization products: Data visualization products cover typical big data display scenarios such as reports, ad hoc queries, online analytical processing, self-service analysis page building, and analysis application sharing, which help enterprise users to improve their data acquisition ability, decision support ability, personalized self-help ability and sharing and collaboration ability under the big data environment.

　　(6) geographic information system and video management product line

　　① City Intelligent Operation Center (IOC): Based on the core technology and platform of Dongfang Guoxin Big Data, the product supports the unified convergence and access of heterogeneous data such as city video, geographic information, three-dimensional data, Internet of Things, structured and unstructured government affairs, and "aggregates, analyzes, controls, applies and displays" the accessed six types of city data through the big data support platform, so as to realize the mining of the value of city data and the more refined management and display of the city.

　　② Urban intelligent video big data platform: adopting video image recognition engine and other technical frameworks to realize access integration, management analysis, mining, judgment and application display of urban video data. It can be applied to video surveillance, portrait recognition, vehicle recognition, event analysis, operation inspection and other systems.

　　After more than 20 years of deep cultivation in the fields of communication, finance, industry, government and public safety, Dongfang Guoxin has accumulated a large number of complete industry solutions covering data, products, platform applications and services.

　　(1) Communication field: The industrial products provided by the company in the main business fields of enterprise operation management, marketing, business decision-making and customer service for operators are business analysis system, precision marketing system, retention system, channel collaboration system, customer perception system, bad information governance analysis system, business support center system, intelligent human intelligence audit system, intelligent anti-fraud and other solutions, which have been widely used in the headquarters of the three major operators and provincial branches.

　　(2) Financial field: At present, the company has formed mobile Internet financial platform, financial big data platform, financial real-time decision-making platform, financial data governance platform, financial cloud computing platform, financial BI application platform, financial Internet core system, financial intelligent marketing platform, financial intelligent risk control platform, Ares technology development platform and other products and solutions in the financial industry, and successfully served nearly 300 banks and financial institutions.

　　(3) Industrial field: The key products provided by the company for the industrial field include:

　　① Industrial Internet Platform (Cloud IIP): As a cross-industry and cross-domain comprehensive industrial Internet platform, Cloud IIP’s core technologies and products are completely independently developed, safe and controllable, providing industrial users with an integrated solution of design, simulation, production, management and service in the whole life cycle.

　　② Energy management platform: The energy management platform uses technologies such as Internet of Things, communication and big data analysis to collect data of meters such as water, electricity and gas at the production site, data of sensors and intelligent gateways, and data of automatic control systems, so as to build a unified energy management and control center, realize energy data collection, analysis and feedback guidance, and help enterprises to save energy, reduce emissions and reduce consumption.

　　③ Ironmaking intelligent interconnection platform: It aims to realize the functions of monitoring, physical examination, benchmarking and online learning, consultation and analysis of blast furnaces in ironmaking enterprises. ④ Equipment Asset Management Platform (EAM): Build an asset life cycle management system based on big data analysis, smooth the relationship between investment, construction, use and scrapping in the process of asset management, establish and improve the supervision and management mechanism of assets, and realize "the accounts are consistent with the facts, the accounts are consistent with the certificates, and the accounts are consistent with the tables".

　　(5) and air compressor management platform, safety production management platform, etc.

　　(4) Government and public security field: The corporate government field mainly provides smart city overall solutions for the whole city, and also provides professional field solutions for all commissions and bureaus.

　　① Smart public security big data platform: with the public security brain as the core, actual combat as the guidance, and intelligence injection as the service model, it realizes keen perception and accurate early warning of various potential risks. Create a multi-functional integrated, multi-police linkage, multi-means convergence of synthetic operational command platform, and provide strong technical support for public security organs to investigate and solve cases, combat and prevent crimes.

　　② Smart Tourism Big Data Platform: By building a tourism big data support platform, three business platforms and n application systems, the balanced development of "smart tourism public service, smart tourism industry supervision and smart tourism format operation" can be realized.

　　③ Smart Transportation Big Data Platform: It is the application of big data, cloud computing and other information technologies in the field of transportation, building an all-weather smart city transportation operation monitoring network and security system, strengthening the intelligent real-time monitoring and emergency command ability covering the whole area of urban roads without blind spots, and improving the emergency handling ability and rapid response ability of urban transportation safety accidents and emergencies.

　　④ Related applications in the field of smart cities: In the field of smart cities, Dongfang Guoxin took the lead in proposing the concept of Urban Intelligent Operation Center (IOC). Dongfang Guoxin Urban Intelligent Operation Center is an integrated and comprehensive product that comprehensively uses modern information technologies such as cloud computing, big data and Internet of Things under the framework of smart cities, and realizes the upgrading and transformation of urban governance system based on urban big data, which can realize digital, networked and intelligent control of urban operation status. Realize accurate management, governance, service and dispatch of cities, evaluate the effect of urban construction, urban management efficiency and urban governance in real time and scientifically, and provide efficient and convenient personalized information services for enterprises and the public while improving government efficiency.

　　⑤ And the government application products of internet plus government affairs and social security big data platform.

　　

　　Third, the core competitiveness analysis

　　The company is a technology-driven big data high-tech enterprise, with a total R&D expenditure of 560 million yuan this year. Through continuous R&D investment, the company’s software product competitiveness and technical service capabilities for multiple industries have been further enhanced. Through a series of core technology research and development, Dongfang Guoxin has become a rare high-tech enterprise in the industry to build a strong technological competitive advantage by independent research and development. During the reporting period, the company’s core technicians and core technologies have not changed significantly, and the scale of core technicians has expanded, mainly due to the introduction of high-end technical talents in the fields of big data technology, big data industry applications, cloud computing, industrial Internet, artificial intelligence and 5G, which further enhanced the company’s technology research and development strength and innovation ability.

　　1. A complete and self-controlled industry-leading new generation IT technology system.

　　Dongfang Guoxin has been focusing on big data business for 20 years. After 20 years of independent research and development, it has now formed five completely autonomous and controllable technical systems with data computing technology as the core. The company’s products have successfully replaced IOE products in many fields and have the strength to replace foreign software manufacturers.

　　(1) Big data technology system: In the field of big data systems and tools technology, the company has the ability to provide data platform construction and operation and maintenance services for customers with a large amount of data. The big data systems, databases, tools and application software stacks involved are all developed by the company; It has the technical accumulation of multi-modal data collection, storage, calculation and service, and can provide various computing engine services for different application scenarios to meet the computing needs of different types and different aging data; It has enterprise-level data quality, data assets and data security management capabilities, and can realize multi-center data operation management across domains and computer rooms.

　　In the field of big data application technology, it provides O2O () integrated, automated and intelligent big data application system construction services for business-oriented enterprises. It can quickly realize the communication of business and data between the middle station and the background system; Standardize online business process formulation through software definition; Help enterprises get through multi-channel product sales and service contacts through data-driven concepts and technologies; Have the ability to develop online systems such as e-commerce platform and mobile APP application; Have the ability of location service, docking with third-party payment, QR code, etc. Have the ability to operate large-scale information mobile APP applications for end users.

　　(2) Artificial intelligence technology system: for telecom operators, finance, insurance, industry, scientific research institutions and other corporate customers, it provides a one-stop collaborative multi-tenant cloud platform for algorithm engineer, data development engineers and business personnel of data science and artificial intelligence, aiming at the problems of high difficulty, high cost and low efficiency, as well as the problems that models cannot be traced back, data cannot be connected, capabilities cannot be called on demand, and computing power cannot be managed in a unified way, so as to open up communication and collaboration among different types of work. Realize the low threshold and high quality development of deep learning model through automatic learning technology combined with low code mode; Improve the training efficiency of large-scale deep learning model by using key technologies of high performance communication protocol; Through the deep learning model compilation and clipping technology, the automatic adaptation of cloud-side heterogeneous computing power is realized, and the automatic collaboration between cloud intelligence and edge intelligence is opened up. It has the ability of video, image, text and voice artificial intelligence algorithm analysis and application system development and construction, and can be integrated with enterprise-level big data application system and use artificial intelligence to empower applications.

　　(3) Cloud computing technology system: provide public cloud, private cloud and hybrid cloud platform construction and operation and maintenance services for government departments and industry customers with big data management needs, and solve the cloud problems of application systems and big data. The company has the ability to build industry public cloud, enterprise private cloud and hybrid cloud; Relying on the self-built cloud computing data center, the standardized public cloud service products of IaaS, PaaS and SaaS are provided in an all-round way, and the network resources are connected to the national Internet backbone direct connection point in one jump, so as to gather and dredge the regional and even national inter-network communication traffic, which can provide high-quality network services for public cloud customers. It supports Bare Metal Server (BMS), provides a dedicated GPU physical server on the cloud, and supports an ARM-structured CPU server, providing abundant computing performance for key application systems, high-performance computing, AI and big data services. Help enterprises realize the rapid migration of application cloud; It is the first in China to realize the cloud heterogeneous data storage computing capability; It is the first in China to realize the ability to build cloud applications based on multi-tenants.

　　Use cloud native technology to enhance the company’s existing big data, artificial intelligence, industrial Internet and 5G communication software, and realize SaaS transformation of data-driven tools and applications on Oriental Guoxin Cloud; Incorporate DevOps concept and process management mode, provide a unified application assembly platform for developers, operators and operators, and simplify and automate application release, delivery and operation and maintenance management. Use the cloud link platform to monitor and analyze the health status of the above-mentioned platform software and applications, analyze and predict problems in a link way and give effective solutions.

　　(4) Industrial Internet technology system: Based on the innovative model of "Big Data+Industry", it integrates cutting-edge technologies such as cloud computing, Internet of Things, big data, mobile internet and artificial intelligence. The platform integrates the collection, access, calculation, storage, service, development and application of industrial data, closely focuses on the concept of creating value for customers, takes data as the basis, takes equipment control and process optimization as the core, and realizes mature solutions covering ironmaking, cement, electric power, energy, manufacturing and other industries, and also covers material formula optimization, production process management, equipment fault diagnosis, process optimization, product quality control and service.

　　(5)5G technology: Facing the strategic development needs of 5G+ industrial Internet, Dongfang Guoxin independently developed 5G small base stations, 5G core networks, 5G edge devices (intelligent gateways and robots) and MEC edge computing platforms. Provide industry customers with 5G private networks through 5G small base stations and 5G core networks, use 5G edge devices to collect sensor data and video data, and sink resources, calculations and applications to the edge of enterprises through MEC edge computing platform. Through the 5G network, 5G edge devices, MEC edge computing platform, combined with Guoxin’s industrial Internet platform Cloudiip, we can realize the collaborative integration of cloud edge networks and provide the overall solution of 5G+ industrial Internet based on the 5G industry private network.

　　2. Cross-industry mass data integration governance, processing and service capabilities

　　As an independent third-party data processing and processing professional company, Dongfang Guoxin Construction System processes 3 trillion pieces of data per day on average, helping customers to query 70 trillion pieces of data, and the maximum size of the big data platform nodes built exceeds 30,000, with real-time response time reaching millisecond level. Using the company’s self-developed data governance and service professional tool suite, as well as many years of modeling theory and experience of large-scale data warehouses, relying on the company’s CirroData cloud database system and big data technology system, we will build a "data cloud" platform product. Thus, a complete cross-industry and cross-domain big data comprehensive management capability, massive data processing capability and reliable processing efficiency have been formed, and PB-level data can also be handled with ease, realizing the realization path from big data technology to data value.

　　3. Empower the application ability of traditional industries with new technologies and new ideas.

　　(1) Closely integrate artificial intelligence with telecom operators, smart cities, finance and other business applications. Use machine learning algorithm to deeply analyze operational data, find business problems in time and adjust business strategies; The deep learning algorithm is used to strengthen the analysis of unstructured data by telecom operators, which greatly reduces the labor cost and improves the efficiency of telecom operators in IT, management, market, network and security. Combining artificial intelligence algorithms with urban scenes, urban life is safer and more convenient through video monitoring and identification technology.

　　(2) Deeply integrate the modeling ability of big data analysis and mining with various industries.

　　(3) Introduce the concept and technology of Low-code development into the field of industrial Internet.

　　(4) The problem of artificial intelligence scene fragmentation is solved by online and offline dual-platform mechanism. Dongfang Guoxin launched "Turing Federation" and "Turing Engine" in due course to realize artificial intelligence landing.

　　4. A variety of end-to-end solutions for big data in industries and fields.

　　The company continued to deepen on the basis of the communication big data platform, and launched a solution for the strategic planning of data center and AI center based on the two products of "Data Cloud" and "Turing Engine"; Digging deep into the value of data, and using artificial intelligence technology to empower customers’ business, a series of AI+ business solutions, such as AI+ business decision-making, precision marketing, customer service, and online transportation, have been formed to help operators continue to innovate and manage their traditional businesses, and improve the level of service refinement; In the financial and insurance fields, marketing cloud, customer insight, precision marketing, customer portrait and other systems have blossomed in an all-round way, successfully expanding a number of important customers, helping customers achieve digital transformation, achieving a double breakthrough in depth and breadth, and achieving a good reputation; In the field of civil aviation, using the company’s accumulated big data technology capabilities for many years, it successfully landed on the airport intelligent data platform and the civil aviation government information system to achieve breakthroughs in the civil aviation field; In the port field, dangerous goods management systems and port big data platforms have landed in many important ports in the country to help customers improve the level of big data and intelligence; In the field of smart cities, we continue to promote the implementation of IOC solutions, covering more than 20 key provinces, cities and regions across the country, and successfully built benchmark projects in North, Shanghai, Guangzhou and Shenzhen; In the direction of digital government, it has obtained Huawei’s "Certified Service Solution Partner Preferred Level" (Preferred Level CSSP) and "Huawei Preferred Solution Partner" certification; A major breakthrough has been made in the field of public security, based on Dongfang Guoxin’s big data products and technical system.In terms of public security structured data processing and data application system, video big data and intelligent AI application system, operational command, public security management and "internet plus" policing, it has fully served the public security field "fighting, preventing, managing, controlling and serving", laying a solid foundation for Dongfang Guoxin to enter the public security field; Dongfang Guoxin Cloudiip Industrial Internet Platform has been selected as one of the top ten cross-industry and cross-domain industrial Internet platforms in China, and has built several regional industrial Internet platforms. In metallurgy, electric power, energy, ironmaking, automobile manufacturing, general equipment and other professional fields successfully landed.

　　5. Experience and ability accumulated in serving major customers in the industry all the year round.

　　Dongfang Guoxin has been deeply involved in the field of enterprise and government informatization for more than 20 years, and has a profound understanding and rich experience in the business forms, business needs and working modes of enterprises and government customers in various industries. The company takes the lead in realizing the strategic layout of big data+industry in the industry. Its business layout covers communication, finance, government, industry, agriculture, public safety and other fields, covering more than 50 countries and serving nearly 1,000 customers. The company serves more than 300 banks, and the share of mobile banking ranks first in China. In telecom, finance, government and other fields, customers have complex business, huge amount of data, numerous IT systems, and the trial and error cost of customer’s big data construction is very high, so the requirements for big data vendors are extremely strict. After more than 20 years of tempering of various large-scale information projects, Dongfang Guoxin has established a perfect three-level customer service system, which ensures the stable operation of customers’ projects in terms of personnel organization, project process control, technical support, standardization of codes and documents, and has set up a variety of service response methods, which can provide customers with remote technical support services, on-site technical support services, full-time technical teams, consulting services and other technical support services. Ensure efficient and high-quality delivery of customer projects. With the leading technology and solutions, the company has played an important role in the business development of customers, won the trust and recognition of customers, and established a long-term strategic cooperative relationship with customers.

　　6, the new intangible assets

　　By the end of the reporting period, the company (including subsidiaries) has obtained 990 software copyrights and 57 patents. During the reporting period, the company added 189 software copyrights and 12 patents.

　　7. By December 31st, 2021, the company had obtained the following important national and industrial qualifications:

　　(1) Oriental Guoxin

　　(2) Shanghai Yitong:

　　(3) yanhuang nova:

　　(4) Beike Yili:

　　(5) Xiamen Tupou:

　　(6) Block nodes:

　　(7) Dongyun Ruilian:

　　

　　Fourth, the main business analysis

　　1. Overview

　　During the reporting period, the company was determined to forge ahead, making steady progress in the traditional market and gaining good news in the new market under the environment of repeated epidemics, showing a strong development momentum. At present, the process of social digitalization is accelerating, and the company has further promoted the application of new technologies such as big data, cloud computing, artificial intelligence, industrial Internet and 5G in the industry, and firmly helped customers to digitally transform. In 2021, the company achieved a total operating income of 2.47 billion yuan, an increase of 18.25% over the same period of last year; Realized an operating profit of 288 million yuan, a decrease of 9.73% over the same period of last year; The total profit was 293 million yuan, a decrease of 12.24% compared with the same period of last year; The net profit attributable to shareholders of listed companies was 302 million yuan, an increase of 0.04% over the same period of last year; The net operating cash flow was 117 million yuan, a decrease of 73.05% compared with the same period of last year.

　　(A) innovation-driven development, brand influence and core competitiveness to further enhance.

　　1. Communication field

　　In China Unicom, the company closely followed Unicom’s comprehensive digital transformation strategy, helping to build the data center, public center and Tiangong system of China Unicom. Following closely the development direction of China Unicom’s business, based on the data center capability, the company fully participated in the IT support construction of Unicom Group’s major reforms such as data access to the cloud, small-scale reform, total customer value marketing, smart customer service and O-domain data base, helping China Unicom consolidate its data center capability, giving full play to the application value of big data, and helping enterprises to reform and develop. Successfully built Unicom Group’s 31-province data uploading project, total customer value marketing platform and O-domain data base.

　　China Unicom’s micro-Wotong project, developed by Beijing Yanhuang Xinxing, a subsidiary, faces the 1.2 billion flow pool of WeChat system and absorbs 100 million powder. Precipitate customer assets for operation, run through the whole process of various businesses, and enhance customer perception. At the same time, we will integrate the capabilities of all platforms of Latong Unicom, connect online and offline consistent experiences, and enhance the OMO system of public channels. Yanhuang Xinxing, as a new manufacturer of the Institute of Soft Research, won the honorary title of "Best Partner in 2021".

　　In (), focusing on the planning and requirements of China Telecom’s digital platform and digital operation, facing the actual management, marketing and service needs of the front line of business, the company continued to help and promote the digital transformation of China Telecom with the strategy of "platform+operation+service". In terms of digital application, the digitalization of marketing services has made substantial progress in Zhejiang, Shanghai, Anhui and other provinces, further empowering data production; The integrated digital grid has gradually landed in Ningxia, Qinghai, Gansu, Shaanxi and other provinces, truly empowering the front line and empowering the digital management and operation of the whole enterprise; Other intelligent manpower, auditing, finance, risk control and other aspects based on M domain are also continuing to be intensively cultivated; Relevant technologies, scenarios and applications have begun to precipitate in O-domain-oriented data acquisition and analysis processing, empowerment management and marketing, and empowerment customer experience, laying the foundation for the next comprehensive empowerment. In terms of data operation, the terminal rights operation at the telecom group level was fully supported by Dongfang Guoxin, forming the company’s own data operation capability, and Liaoning Telecom also successfully signed the first cooperative operation order of the province.

　　In (), under the background of China Mobile’s digital transformation and domestic substitution, the company followed the strategic planning of China Mobile’s big data domain, accelerated the layout of the headquarters-level centralized big data platform and the project construction in related fields, and further stabilized the position of China Mobile as a core supplier in the field of big data construction. The company continues to build big data+and AI+ ecological projects, extending the data center capability to business applications, and accelerating the transformation process of traditional business applications. Relying on the base and capabilities of the data center, we have built professional warehouses for traditional business applications, especially in the fields of customer service, risk prevention and control, and internal audit. At the same time, combined with the empowerment of AI+ business scenario mode, we have achieved breakthrough results in related businesses and quickly formed scale advantages. With the acceleration of domestic substitution process, products such as BEH, stream development and processing engine, data collection and analysis platform and data development and governance platform developed by Dongfang Guoxin were successfully listed in China Mobile’s IT direct acquisition catalogue, while CirroData database, a self-developed core product, was listed in China Mobile’s information innovation product catalogue. The company will realize the dual-track development of customized service and product service in China mobile market, and continuously enhance the position of Dongfang Guoxin in China mobile market through the dual-track drive of business and product scale.

　　2. Financial field

　　During the reporting period, the company has formed core products and solutions such as financial big data system, big data application system, financial cloud computing system, financial artificial intelligence system, mobile internet system and internet financial system in the financial industry, and successfully served nearly 300 banks and other financial institutions. The company has successfully cooperated with many banks and financial institutions in distributed database, data lake, data middle platform, business middle platform, Internet middle platform, cloud computing, artificial intelligence, mobile internet, and innovation ecology, showing the company’s business expansion ability and overall strategic layout in the financial field.

　　At present, China’s domestic database market is very active. CirroData, a distributed cloud database independently developed by the company, has solidly promoted technology research and innovation, iteratively optimized product solutions, and actively built the industrial ecology of Xinchuang, and has made remarkable achievements in the financial industry, industry migration and application, and ecosystem construction. At present, it has cooperated with a number of policy banks, national joint-stock commercial banks, city commercial banks and other financial customers. During the reporting period, the number of new CirroData deployment nodes doubled. At the same time, the company is committed to the market expansion of the securities industry, and has achieved good cooperation with financial institutions such as enterprises under the China Securities Regulatory Commission and CSI in the field of distributed databases and big data.

　　In the field of financial big data, in addition to distributed databases, the company has also continuously cultivated core products and solutions such as big data platform, big data warehouse, data lake, lake warehouse integration and data center platform. In 2021, the company and domestic head city commercial banks have achieved innovative cooperation in the field of data lake and lake warehouse integration, setting an industry benchmark; In the field of big data applications, based on the core product marketing cloud and sales cloud, the company has successively built marketing business middle platforms for a number of head commercial banks, which serve as the "new engine" for financial institutions’ profit growth, enabling digital marketing and intelligent operation. At the same time, the company has successively launched marketing cloud and sold cloud products for credit card centers of two national joint-stock commercial banks, and vigorously developed the credit card market. It is expected that in 2022, it will be able to achieve strategic cooperation with more credit card centers of commercial banks; In the field of mobile internet, the company continued to maintain its market advantage, and the cumulative number of cases ranked first in the country. During the reporting period, it achieved in-depth cooperation with the largest trust company in China on customer apps and mobile development platforms, creating a benchmark project for the subsequent expansion of the trust market; In the field of Internet finance, the company has achieved strategic cooperation with a large city commercial bank, completed the reconstruction of its original online banking system and built the Internet middle platform capability, creating an application platform integrating intelligent operation and customer ecology, which not only brings new user experience to end users, but also is an important layout for bank customers on the road of digital transformation; In the fields of cloud computing and artificial intelligence, the company continues to be committed to combining core products with financial scenarios.In the financial leasing industry, the application case of "Oriental Guoxin Public Cloud" was launched for the first time, and the artificial intelligence product Turing Engine was also used in many financial institutions. I believe that in the future, we will provide the best services for more financial institutions in the fields of cloud computing and artificial intelligence.

　　During the reporting period, the sales revenue of Shanghai Yitong Information, a subsidiary, was about 468 million, a year-on-year increase of 22.2%. The net profit was about 57,393,000, a year-on-year increase of 3.0%. Yitong Information continues to maintain technological and business innovation, and based on the traditional mobile marketing and mobile exhibition industry, it builds a unified App portal for all employees of the Bank, helping the bank to carry out digital operation transformation, and landing business and applications with projects such as Bohai Bank’s "Pocket Bohai" and Beibu Gulf Bank’s "Digital Work Platform"; Further expand and deepen the development of enterprise online banking and its App application to Internet and enterprise eco-banking, and at the same time integrate traditional enterprise finance to provide enterprises with all-round financial services, scene services and ecological services, and successfully landed in Zhejiang Rural Credit Cooperative’s "enterprise interconnection" and other projects; Actively respond to the rural revitalization strategy put forward by the 19th National Congress, cooperate with banks to combine rural industrial finance, inclusive finance, rural government affairs and other practices, and help the development and construction of digital villages’ App. The applications cover rural governance, urban-rural integration, neighboring mutual assistance, agricultural product revitalization, credit construction, convenient living and other specific applications of inclusive finance; Promote and popularize the construction of small program ecological development platform based on Ares technology platform, provide small program development technology platform for banks under the premise of "standardization, standardization and componentization", and realize "one-end development and multi-end deployment" to WeChat applet, Alipay applet, Tik Tok applet and Ares applet platforms, so that banks can integrate more business innovations and services by providing an open ecosystem of small program matrix.Build and enrich the financial ecology; The existing businesses and products such as "CRM+" and marketing platform, which are widely praised and promoted by banks, are still remarkable business highlights of the company in the past year.

　　During the reporting period, the company continued to explore new business value in the insurance industry, and expanded the breadth and depth of insurance business: precipitated high-reuse solutions and products such as data center and CRM, and quickly implemented them in small and medium-sized life insurance and property insurance companies with high quality, and continued to promote the construction and application of three products, namely data center, business center and business front desk, to help the digital transformation of insurance enterprises. In 2021, the company advanced into the fields of insurance data center, CRM, core system, etc., and achieved key market breakthroughs. Won the Hengan Standard Life Data Center Project for the first time, and built a data center integrating data layered construction, data governance and data service, so as to export "fast, accurate, comprehensive and intelligent" data service capabilities for insurance companies; Then win the CRM system project of Everbright Life Insurance, build a CRM intelligent system with systematic labeling, standardized service and application platform, and realize insurance technology empowerment and data empowerment; Third, win the China Xinbao trade insurance core system project, build a new generation of trade insurance core business system, support the whole process operation of trade insurance business, and gradually implement the digitalization of core business processes.

　　China’s financial industry Xinchuang has entered the stage of high-quality and all-round development, and the market space is huge. As the fastest-growing innovation field in the industry, finance has entered a period of rapid growth, and the demand for the field has been continuously released and verified by the industry. As the pillar of the financial industry, the banking industry is also the "vanguard" of financial innovation. In the field of financial innovation, the company has been committed to the construction and improvement of the innovation ecosystem, and has invested heavily in the R&D resources of innovation in the fields of databases, application software and cloud services. With a mission, Dongfang Guoxin continues its independent research and development and deep cultivation in the industry, facing more users and exerting greater value.

　　3. Industrial field

　　(1)Cloudiip platform technology and support service capabilities continue to improve.

　　In the selection of the national cross-industry and cross-domain industrial Internet platform of the Ministry of Industry and Information Technology in 2021, the Cloudiip platform of Dongfang Guoxin continued to maintain its leading position, and Dongfang Guoxin has maintained the forefront of the national industrial Internet dual-span platform for many years. During the reporting period, the Cloudiip platform further strengthened the four capabilities of platform foundation, application, ecology and industrial integration, continuously upgraded the platform supply capacity, and quickly and iteratively integrated the latest technical tools to support flexible data analysis, model construction, micro-service and APP design, etc., and the intelligent development capability of Cloudiip was greatly improved.

　　(2) The release of "peak carbon dioxide emissions Carbon Neutralization" management platform.

　　One of the key problems solved by the company’s industrial system products is to reduce energy consumption and improve energy utilization efficiency, which is highly consistent with the national double-carbon strategic goal. Especially in the process industries with high energy consumption such as electricity, coal and cement, Dongfang Guoxin has accumulated a large number of mechanism models, data models, expert models and monitoring platform products, providing effective help for enterprise production control and early warning. In 2021, Dongfang Guoxin’s energy consumption edge monitoring equipment will be applied in many provinces, cities and industries. On July 11th, 2021, the company and Chongyang Financial Research Institute of Renmin University of China jointly released the world’s first "peak carbon dioxide emissions Carbon Neutralization" intelligent monitoring and management platform. Based on the top-level design advantages of think tanks, the "Double Carbon" regulatory platform builds 12 specialized and refined regulatory indexes, including total carbon emissions, carbon sinks, peak carbon dioxide emissions achievement rate, carbon neutrality achievement rate and carbon intensity, so as to promote the modernization, transformation and upgrading of the "peak carbon dioxide emissions, carbon neutrality" governance system and governance capacity.

　　(3) New breakthroughs have been made in promoting industrial intelligence.

　　Dongfang Guoxin expert team combines professional theory and practical experience in the industry field with the company’s big data capabilities and industrial Internet platform to deeply expand the application in the industry field and help the digital transformation of enterprises. In 2021, Dongfang Guoxin achieved new breakthroughs in new energy, electric power, thermal power, cement, coal, heating and other industries.

　　In the field of new energy, Dongfang Guoxin can provide customers with overall new energy solutions, including: new energy data asset planning and governance system construction, new energy big data center construction, new energy specific scenario application prediction and deviation analysis, etc., and can quickly export five core solutions such as smart wind power, smart photovoltaic, comprehensive new energy, smart energy storage and smart energy service to customers, and form big data scenario application products such as health diagnosis, smart security, early warning of equipment and integrated analysis platform for distribution and transmission. Dongfang Guoxin and Huaneng Qingneng Institute signed a strategic cooperation agreement around "Research on New Energy Product System", and carried out in-depth cooperation with well-known domestic enterprises such as Hebei Electric Power Research Institute, Huaneng Clean Institute, Three Gorges New Energy and Jilin Electric Power Research Institute. Dongfang Guoxin participated in the construction of the comprehensive exhibition system of "Green Olympics and Low Carbon China" in Zhangjiakou, State Grid. Through the combination of static data and dynamic data and the linkage of real scene and virtual model, it showed the achievements of State Grid Hebei Company in the direction of renewable energy development and low carbon development, created a typical demonstration of source, network, Netherlands, storage and comprehensive management, and provided government departments with many application products such as energy supervision, energy planning, meteorological early warning and a "comprehensive window for green Olympics".

　　In the field of thermal power, Dongfang Guoxin has built a series of smart power plant solutions, including intelligent operation optimization, intelligent alarm, intelligent analysis and diagnosis of digital twins, intelligent safety management, intelligent equipment management, emergency command management, intelligent operation management, etc., which has realized the centralized monitoring, scene reproduction and unified supervision of subordinate thermal power enterprises on the group side, and helped the group to develop harmoniously in low-carbon environmental protection, innovation drive, quality benefit and safe production. Together with North China Electric Power Research Institute, Guoshen Group, Jiujiang Power Plant of National Energy Group, and Huanghua Port of National Energy Group, we have completed the development and optimization of 18 "equipment management" models. Through sinking the power plant by Electric Power Research Institute, we have optimized the operating conditions of power plant equipment, improved the equipment performance, and helped the power plant to save energy and reduce consumption.

　　In the field of cement, the construction project of comprehensive big data platform has been started, and the control and optimization application system of Dongfang Guoxin Cement has landed in leading enterprises in Tapai, Jinyu, Shanshui Cement and other industries. Construction of the development and application project of cement factory-level integrated management and control platform based on industrial internet architecture in Chengde Jinyu, laying a solid foundation for the replication and promotion of big data platform in cement industry; Through the platform construction of () Group and three regional factories, the two-level architecture model of Dongfang Guoxin’s comprehensive big data platform in the cement field has been enriched.

　　In the field of coal, comprehensive data monitoring and management products such as coal big data platform, monitoring and early warning, coal mine map, etc. and digital twin and automatic control system of roadheader working face have been successively launched, and customers in Bayangaole Coal Mine, Shuangxin Mining and other industries have landed. The platform empowers the working face equipment group to have the ability of independent perception, independent decision-making and automatic control operation, which can realize the real scene reproduction of tunneling working face and the autonomous navigation of tunneling main and auxiliary machines. Multi-machine coordinated control and remote centralized control of back-up equipment such as crusher and belt conveyor effectively improve the management level, production efficiency and safety guarantee ability of tunneling operation, realize intelligent reduction of staff and increase efficiency, and comprehensively promote the intelligent construction of coal mines.

　　In the field of coal chemical industry, the construction of information management system for chemical production in Xinjiang has been completed, and several functional modules developed have achieved good application results in enterprise production and management. The first intelligent management system for methanol synthesis catalyst jointly established with Xinjiang Chemical Industry has also been running stably, which has achieved remarkable results in improving catalyst health, reducing harm and optimizing performance, and has also made outstanding contributions in improving yield, reducing energy consumption and reducing carbon emissions.

　　(4)AI technology and industrial safety production are deeply integrated.

　　In 2021, Dongfang Guoxin AI visual identification project covers many fields such as energy, electric power, coal, wind power, chemical industry, etc. Five application scenarios of industrial visual identification are summarized and defined: intelligent inspection, on-site safety, industrial quality inspection, fault diagnosis, unattended coverage, intelligent inspection, equipment fault detection based on thermal imaging identification, X-ray flaw detection and quality inspection identification, personnel behavior safety management, equipment leakage, equipment condition monitoring and other industrial scenarios.

　　The edge product of "Industrial Visual Identification Management Platform Based on Multi-source Data Fusion" independently developed by Dongfang Guoxin allows customers to quickly access video data sources, algorithm binding, alarm rule setting and interface subscription, and realize self-built industrial visual identification applications. Dongfang Guoxin chemical industry artificial intelligence remote inspection solution has been selected into the list of outstanding cases of smart security solutions in 2021 selected by relevant industrial centers.

　　In the field of mining the value of industrial data, Dongfang Guoxin continuously obtains intermittent results by establishing OE industrial brain, integrating mechanism model, expert model, statistical model and big data model based on pre-parameters and process variables, and by means of data cleaning, dimensionality reduction, correlation analysis and supervised learning, providing effective online analysis means for production and operation, realizing comprehensive perception at any time, any place and any environment, so as to participate in control in advance and increase the yield. Using low-configuration edge computing front end, reliable support can be provided for the field through small samples. Support customized agile development, adjust applications according to on-site business scenarios, and quickly change parameter types and user interaction. The accuracy of the model is high, and the accuracy of the results is over 96% in the actual use process.

　　(5) internet plus industrial production safety, promote industrial intrinsic safety.

　　In 2021, based on the advantages of its own industrial Internet platform, Dongfang Guoxin built an industrial intrinsic safety platform through the integration of industrial data and algorithms. Based on production data and environmental data, it established a real hazard model through big data and AI algorithm, and reduced the dimensions of the spatial and temporal attributes of the real hazard model, and finally realized the quantitative safety assessment of the region and pushed the safety index. In the usual monitoring process, parameter monitoring is changed to state monitoring, which reduces the operation difficulty and management cost, increases the effective management scope, and can better serve the production plant. Even the administrative staff can quickly grasp the safety risk data through quantitative evaluation, which provides effective safety management tools for the group and government customers.

　　Dongfang Guoxin Intrinsic Safety Platform focuses on monitoring and prevention, and the monitoring area includes four states. In sub-health state, relevant early warning is carried out in advance to ensure production safety as much as possible, and industrial data, artificial intelligence and safety production are organically combined in the way of "monitoring in peacetime and commanding in wartime", which provides effective support for industrial safety and platform support for national digital industrialization.

　　4. Government and other fields

　　During the reporting period, the company maintained sustained growth in the direction of city brain (IOC) and government big data, and added projects such as Changyi smart city and smart community. The company actively landed and expanded the direction of smart culture and art, achieved excellent results in the information integration project of communist party Historical Exhibition Hall in China, and won the first prize of the first new smart city innovation and application competition. In the field of foreign cooperation, we will continue to expand business cooperation with Huawei and other partners in the field of smart cities, and actively expand cooperation in the field of smart rail transit. The company actively responded to the requirements of the state on the digital transformation of state-owned enterprises, reached a strategic cooperation agreement with Beijing Safe Housing Center Co., Ltd., and provided integrated overall solution services.

　　During the reporting period, the company actively participated in the "Tenth Five-Year Plan" in the field of public safety, solidly promoted the research and development of public safety featured products and accumulated experience in featured fields, and successfully completed the transformation and application of platforms such as data governance, knowledge map and science cloud in the field of public safety; On the basis of successfully completing the customs risk management system, the new generation customs clearance management system, the big data pool resource management platform and the Anke project of the General Administration of Customs, the company continued to deepen the implementation of customs data governance and ETL and other related projects; The company signed the data governance and digital transformation application of Fenjiu Group and the technical service of sichuan-tibet railway data governance service, and used the company’s rich experience in the field of big data to help traditional enterprises effectively carry out information transformation and upgrading. The company has made steady progress in the transportation industry, built the foundation of Hebei Airport Group’s data center platform, service bus, passenger service and other capabilities, and formed an integrated airport big data platform solution and construction capability covering data collection, data storage, data calculation, data governance, data service and data application.

　　5. Public cloud domain

　　During the reporting period, Dongfang Guoxin Cloud entered the accelerated growth channel, especially the business in intelligent cloud grew rapidly. Dongfang Guoxin Cloud technology goes deep into operators, traditional industries and government service departments, helping thousands of industries to integrate innovation and improve efficiency. After more than a year of technical precipitation and market polishing, the company has continuously iterated over the public cloud and private cloud product systems, combined with the company’s layout in the data center field, to build the intelligent cloud ecosystem, and functional products such as cloudy management, cloud migration and cloud private line have been launched one after another, which has further strengthened the competitiveness of Dongfang Guoxin Cloud in the market and defined our strategic direction in the field of cloud computing. At the same time, with the development of Xinchuang industry and the demands of broad users, Dongfang Guoxin Cloud also supported the virtualization function of ARM architecture servers in 2021, and adapted more independent controllable software and hardware manufacturers, and launched a series of functions such as ARM chip virtual machine and bare metal in BoncStack private cloud products.

　　With the rise of hot concepts such as artificial intelligence and meta-universe, and with the help of the policy of "east counting and west computing", the market demand for computing power has also reached the climax of explosive growth. A large number of customers have an unprecedented strong demand for computing power in artificial intelligence, wisdom+fields, and so on. For this reason, the company has invested a lot of technical strength in the research and development of GPU virtualization, GPU transmission and other products. The year of 2021 is a year of rapid development of Dongfang Guoxin Cloud, and the company has obtained more qualifications in cloud security, trusted cloud, container cloud platform, research and development of soft works, etc. The company’s cloud business has also entered a period of accelerated growth, creating many benchmark cases in the military, industrial manufacturing, government and public security fields. At the same time, the continuous investment in technology has enabled Dongfang Guoxin Cloud to provide better protection and support for data-driven enterprises and help enterprises to transform digitally.

　　(2) Complete the non-public offering to enhance the company’s core competitiveness and profitability.

　　As a company with pure big data genes, Dongfang Guoxin’s layout of cloud computing and artificial intelligence comes down in one continuous line. Since its listing, the company has closely followed the development direction of the world’s most advanced technologies, conducted in-depth key research and development in the directions of big data, cloud computing, artificial intelligence and industrial Internet, and continuously incubated company-level core technologies and products, which has already taken the first-Mover advantage in these fields. The funds raised this time are used for the industrial Internet cloud intelligent platform, the 5G+ industrial Internet converged access and edge computing platform, and the Oriental Guoxin Cloud project, and the company’s working capital is appropriately supplemented. With the completion and promotion of the fundraising project, the company’s independent research and development capability will be further enhanced, the company’s technology and product industry application capability will be greatly improved, the company’s product, technology and solution capabilities in the fields of cloud services, 5G+ industrial Internet will be strengthened, business model innovation will be promoted, and stronger support will be provided for the company to consolidate its position in the industry and expand its market, thus improving its business scale and market space. Through this non-public offering, the company will enrich its capital strength, improve its ability to resist risks, fully consolidate its core competitiveness, further enhance its value, enhance its profitability and better repay all shareholders of listed companies.

　　(III) The company won many awards, and its brand reputation and influence continued to improve.

　　During the reporting period, the company and its subsidiaries won many honors. Including "2021 Beijing Software Core Competitiveness (Scale Enterprise)" evaluated by Beijing Software and Information Service Industry Association and "Top 100 Comprehensive Strength of Beijing Software and Information Service Industry" for five consecutive years, "2021 Digital Expo Leading Scientific and Technological Achievement Award" of China International Big Data Industry Expo, "Beijing First batch of" Invisible Champion "enterprises jointly issued by Beijing Economic and Information Bureau and Beijing Federation of Industry and Commerce, The Top 50 Big Data Enterprises in China in 2021 selected by China Big Data Alliance and other institutions, the TOP500 and TOP100 Leading Enterprises in China Xinchuang Industry in 2021 jointly released by Internet Weekly and eNet Research Institute, the Top 100 Pioneer List of Industrial Internet released by the judging panel of Industrial Internet World, and the Unicom Smart Service Project Center won the "Best Partner" award.

　　(4) Strengthen refined operations and continuously improve operational efficiency.

　　During the reporting period, the company continued to adopt the combination of budgeting and refined management, adhered to the management mode of paying equal attention to humanities, and constantly optimized the management process and internal control system. In terms of operation management, through continuous improvement and accumulation, the company’s operation management platform gradually plays a role. The company further strengthens the role of digital operation, and accurately analyzes each level and position with multi-dimensional portraits of sales, pre-sales and project implementation, providing a basis for the company’s awards, accurate assessment, avoiding blind waste, and further improving the company’s digital operation and digital assessment capabilities; In the formulation and assessment of the overall performance of the department, the full-cost cash flow accounting is carried out, the process tracking evaluation is strengthened, and the cost management is more comprehensive and accurate; In terms of employee performance and training, we will improve the technical certification system for initial, intermediate and advanced R&D products, and comprehensively enhance the vitality of employees and grassroots organizations.

V. Prospect of the Company’s Future Development

　　(A) the company’s development strategy

　　With the advent of the era of "digital economy and intelligent economy", data has become an important strategic resource of the country. In recent years, accelerating the construction of new infrastructure such as 5G, big data center, industrial Internet and artificial intelligence has become a major national development strategy. With the increasing support of "new infrastructure" policy, the development speed of the industry will be greatly improved. In 2020, the company formulated a strategic plan for the next five years: continue to focus on the fields of big data, cloud computing, artificial intelligence and industrial Internet, and deeply empower customers in various industries for digital transformation. The company will comprehensively promote the cloud-based strategy of Dongfang Guoxin, and provide cloud-based software and services for a large group of small and medium-sized enterprise users based on many big data, AI and other software products that have been deposited by head customers in large-scale industries for many years; Promote the independent packaging and sales of many outstanding technical products such as CirroData database, data science cloud platform, data governance platform BDG and enterprise big data platform BEH, and cultivate customers’ habit of paying separately for software products; The company will keep the focus and patience of strategic direction, constantly innovate actively, strengthen the technical moat of the company, and promote the ecological strategy of "product+platform+service" from the model with "project" as the core, bringing more economic benefits to the enterprise and creating greater social value at the same time.

　　(II) The Company’s business objectives and business development plan for 2022.

　　In 2022, the company adhered to the overall business idea of "integration, focus, deep cultivation and efficiency improvement", maintained strategic focus and determination, and continued to build the core competitiveness of Dongfang Guoxin in the laid-out areas, accumulating and grasping the market opportunities brought by the digital tide, enabling customers’ digital development and achieving steady growth of the company’s performance.

　　1. Strengthen business focus, and make business deeper, wider and stronger.

　　In 2022, the company will continue to focus on the research and development direction of big data, industrial Internet, 5G, cloud computing and artificial intelligence; Focus on communications, finance, industry, government and cloud services; Focus on industry customized development software and services, standardized products, and cloud application services. The company will deeply cultivate industry customers, technology research and development and customer needs. Focus on the existing market, create superior solutions and expand the leading edge of the industry; Break through technical barriers and rely on advanced technological advantages to break through the bottleneck of business development; Understand customer needs and solve customer pain points. Accelerate the sales of technology productization and cloudization, and further strengthen the effective integration of business, technology and solutions between parent and subsidiary companies; Strengthen the integration of the company’s R&D products and user experience. Strengthen publicity and sales, improve product sales and marketing systems, and accelerate the transformation and landing of research and development results.

　　2. The industrial Internet platform has been continuously upgraded to empower the digital transformation of the industrial economy.

　　In 2022, based on the Cloudiip platform, Dongfang Guoxin will integrate the new generation information technologies such as big data, cloud computing, Internet of Things, artificial intelligence and 5G with the needs of industrial enterprises to build N functional general platforms such as machine vision, intrinsic safety and data value mining, which will continue to be promoted in N industrial fields such as electric power, cement, chemical industry, coal and ports, give play to the effectiveness of industrial Internet and deepen its influence.

　　As a double-span platform selected by the Ministry of Industry and Information Technology, Cloudiip will further strengthen the support and operation of cloudization, continue to study and overcome the processing problems of industrial big data, improve the capabilities of industrial data collection, standardization, timeliness and data governance, and strengthen the research and development and pilot application of 5G private networks. In the direction of small and medium-sized enterprises, we will build cloud-based data collection and application services for small and medium-sized textile, motor, machine tool and other manufacturing factories, reduce the construction cost of enterprise platforms, promote the popularization of industrial Internet platforms, build ecological platforms, and strive to become an industrial Internet platform with international influence.

　　3. Cloudization business has clear strategic objectives and is ready to go.

　　In 2022, the important strategy of Oriental Guoxin Cloud is "based on cloud computing, focusing on important tracks with artificial intelligence as the starting point", and cloud +AI is closely integrated, and "integration of cloud and intelligence" has become the unique competitive advantage of Oriental Guoxin Cloud. It has developed into a technologically advanced AI production platform with integrated software and hardware. In addition, Dongfang Guoxin Cloud fully integrates core technologies and platforms such as voice, vision, knowledge map and intelligent operation and maintenance of root cause analysis, empowering new infrastructures in all walks of life and providing strong support for enterprise innovation.

　　4. Continuously improve operational efficiency and optimize talent management.

　　In terms of human resources, in order to activate organizational vitality, the long-term development of enterprises needs to continuously deliver fresh blood, and the company gives clear and specific indicators in terms of talent flow and reserve young cadres, and boldly promotes outstanding talents; In terms of company operation, in order to improve operational efficiency, we will further improve the management system and assessment system. Through the company’s operation management system, everyone and every penny can be reflected in the process, and the company’s operation mode can be moved forward to the project or project group level, with a single project or project group as the smallest operation unit, the management level can be shortened, so that the company’s resources can be tilted to the front line, which is convenient to meet customers’ needs quickly, thus realizing the improvement of the company’s overall operation efficiency. In terms of corporate culture construction, we will vigorously promote corporate culture, publicize the company’s policies and systems, and convey the company’s business ideas to every grassroots employee.

The Central Meteorological Observatory continued to release at 18: 00 on November 6.Strong wind blue warning, cold wave blue warning, blizzard orange warning:

It is estimated that from 20: 00 on November 6 to 20: 00 on November 7, some areas in central and northwestern Inner Mongolia, eastern Xinjiang, northern and eastern Qinghai, Hexi, Gansu, Heilongjiang, Jilin, Liaoning and other places will have strong winds with gusts of 7; There will be strong winds of magnitude 7-8 and gusts of magnitude 9 in the eastern Bohai Sea, the Bohai Strait, most of the Yellow Sea, the northern part of the East China Sea, the southern part of the East China Sea, the Taiwan Province Strait, the east of Taiwan Province, bashi channel and parts of the northeastern South China Sea, among which there will be strong winds of magnitude 9 and gusts of magnitude 10 in some parts of the eastern Yellow Sea.

Affected by strong cold air, it is estimated that from 20: 00 on November 6 to 20: 00 on November 7, the temperature in southeastern Inner Mongolia and most parts of Northeast China will drop by 6 ~ 8℃ successively, among which the temperature in some parts of eastern Jilin can reach 10 ~ 12℃. The lowest temperature 0℃ line will be located in the northeast of Hebei, Tianjin, southwest of Shanxi, Guanzhong Plain of Shaanxi and southeast of Gansu. Some areas in central and northwestern Inner Mongolia, eastern Xinjiang, northern and eastern Qinghai, Hexi, Gansu, Heilongjiang, Jilin and Liaoning will have strong winds of 5~6 and gusts of 7; There will be strong winds of 7-8 grades and gusts of 9-10 grades in the eastern Bohai Sea, most of the Yellow Sea, the northern part of the East China Sea, the southern part of the East China Sea and parts of the northeastern South China Sea.

It is estimated that from 20: 00 on November 6 to 20: 00 on November 7, there will be heavy blizzards in parts of northern Jilin and central and eastern Heilongjiang, among which there will be heavy blizzards (20 ~ 24 mm) in the northeastern part of Heilongjiang. The depth of newly added snow in some areas above is 2-10 cm, and the local area can reach more than 12 cm.

The cold wave continues,

Everyone should take precautions.

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The cold wave struck,

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　　Xinhuanet Beijing, October 23 rd (Xinhua News Agency "Xinhua Viewpoint" reporters Zhou Tingyu, Zhang Jingyang, Zou Shengwen) People eat for the sky. Sanlu brand infant milk powder incident shocked the world, and also made the draft food safety law in the third trial in the National People’s Congress Standing Committee (NPCSC) more concerned. People are saddened by the "Sanlu incident" and can’t help but ask: What can we use to ensure our most basic need-food safety? Can food safety legislation prevent the "Sanlu incident" from happening again?

　　Liu Xirong, vice chairman of the Law Committee of the National People’s Congress, pointed out on the 23rd that in view of the Sanlu incident, the draft food safety law was revised in eight aspects, so as to prevent and deal with such major food safety accidents from the legal system.

　　Highlight the whole process of supervision and emphasize the responsibilities and communication and cooperation of local governments and departments.

　　The investigation of "Sanlu incident" found that the problem milk powder was caused by the addition of melamine by criminals during the purchase of raw milk. However, after the incident, the "milk station" in the raw milk purchase process was not clearly regulated by which department, and the supervision of the source of milk powder production was a blank.

　　In some places, there are some problems in subsection supervision, such as lax division of labor, multiple law enforcement, unclear responsibilities, and "broken" supervision chain. Therefore, the third draft of the draft food safety law emphasizes the responsibilities of local governments and relevant departments and highlights "full supervision and management", that is, there can be no gaps from the source to the table.

　　The draft stipulates that the local people’s governments at or above the county level shall organize and coordinate the food safety supervision and management in their respective administrative areas, establish and improve the coordination mechanism for food safety supervision and management, and implement the whole process of food safety supervision and management.

　　The local people’s governments at or above the county level shall, in accordance with this Law and the provisions of the State Council, determine the food safety supervision and management responsibilities of the health administration, agricultural administration, quality supervision, industrial and commercial administration and food and drug supervision and management departments at the corresponding level. The relevant departments shall be responsible for the supervision and administration of food safety within their respective functions and duties.

　　At the same time, the draft also adds provisions that the above departments should strengthen communication and close cooperation, exercise their functions and powers according to law and assume responsibilities according to their respective division of responsibilities.

　　The person in charge of relevant departments in the National People’s Congress Standing Committee (NPCSC) said that during the second trial of the draft, Committee member the National People’s Congress Standing Committee (NPCSC) suggested that the supervision responsibilities of some local departments were unclear and the cooperation was insufficient, and the system of food safety supervision should be further clarified. After the "Sanlu incident", the whole society has higher requirements for establishing a supervision system that can truly ensure food safety and ensure public health.

　　"In order to truly realize effective supervision and prevent such serious food safety accidents from happening again, we should plug the loopholes in supervision from the legal system and establish a supervision system that is administrative according to law, coordinated and efficient, consistent with powers and responsibilities and clear in accountability." The person in charge said.

　　Control the spread of accidents as soon as possible and strengthen the monitoring and evaluation of food safety risks.

　　According to media reports, as early as March this year, consumers reported the quality problems of Sanlu brand infant milk powder to the relevant departments, but they did not pay enough attention to it. It was not until September that they began to deal with it as a problem. The failure of the early warning mechanism is one of the major problems exposed by the Sanlu incident.

　　Liu Xirong said that in order to facilitate the timely detection of potential safety hazards in food and take corresponding management measures to deal with them, the third draft of the Food Safety Law added provisions to strengthen food safety risk monitoring and assessment:

　　-the State Council agricultural administration, quality supervision, industrial and commercial administration and the State Food and Drug Administration and other relevant departments shall immediately notify the health administrative department of the State Council after learning the information about food safety risks. After verifying the information, the health administrative department of the State Council shall timely adjust the food safety risk monitoring plan.

　　—— If the health administrative department of the State Council City finds that there may be potential safety hazards in food through food safety risk monitoring or receiving reports, it shall immediately conduct inspection according to law and conduct food safety risk assessment.

　　Relevant persons pointed out that in food safety supervision, the risk monitoring and evaluation of food safety is a front-end system, which is a technical and basic system to prevent food safety accidents. This is also a relatively common system in the world.

　　This draft emphasizes in particular that, after learning the information of food safety risks, the health department should adjust the risk monitoring plan in time to monitor the signs of risks; At the same time, it emphasizes the seamless connection between risk monitoring, risk assessment and follow-up inspection system.

　　According to the requirements of the draft, once food hidden dangers are discovered, measures should be taken immediately, and they cannot be left unchecked. "If the early warning system can play an effective role, the food safety problem in Sanlu will not spread to such a serious extent and cause such a big loss." The person concerned said.

　　Strengthen the revision and use supervision of food additive standards

　　Melamine is a slightly toxic chemical raw material, not a food additive, but it has been added to dairy products by criminals. Inadequate monitoring of illegal use of additives and the addition of illegal substances is one of the important reasons leading to the Sanlu incident.

　　In order to prevent the irregular use and abuse of food additives and ensure the safety of food sources, the third draft of the Food Safety Law has made corresponding provisions on the production and operation, catalogue scope, use and label of food additives. Among them, two special provisions have been added:

　　-The administrative department of health of the State Council shall, according to the results of food safety risk assessment, revise the standards of varieties, scope of use and dosage of food additives in a timely manner, and only those that have been proved to be safe and reliable and technically necessary after risk assessment can be included in the permitted range of food additives.

　　-Food producers shall use food additives in accordance with the provisions of food safety standards on the varieties, application scope and dosage of food additives, and shall not use chemicals other than food additives or other substances harmful to human health in food production.

　　Relevant persons believe that the supervision of food additives is an important aspect of the revision of the draft food safety law. According to the new regulations, even harmless substances are not listed in the catalogue and are not allowed to be added to food.

　　Perfecting the food recall system and emphasizing the responsibility of the government in the recall

　　Since March this year, Sanlu Group has received some complaints from consumers suffering from urolithiasis, and the group has also carried out some investigations, but failed to take effective measures in time, which led to the expansion of the situation. It was not until September that Sanlu Group recalled some market products and sealed the products that had not yet left the warehouse.

　　According to the provisions of the second draft of the Food Safety Law, food recall is an independent behavior of enterprises, and enterprises should take the initiative to recall their own food when they find something wrong. When a sales operator finds a problem, he shall immediately notify the producer to recall it.

　　In this regard, some members of the National People’s Congress Standing Committee (NPCSC) suggested that the implementation of the food recall system should not only rely on enterprises’ consciousness, but also emphasize the responsibility of the government. In the case that enterprises do not take the initiative to recall, the government should order enterprises to recall unqualified food.

　　To this end, on the basis of stipulating that enterprises should take the initiative to recall and deal with the problem products, the third draft of the draft has added the stipulation that enterprises should report the food recall and treatment to the quality supervision department at or above the county level.

　　The draft also emphasizes the responsibility of the government in the recall. The draft stipulates that if food producers and business operators fail to recall or stop operating foods that do not meet food safety standards in accordance with the provisions of this law, the quality supervision and industrial and commercial administrative departments at or above the county level may order them to recall or stop operating.

　　The draft also makes relevant provisions on the recall system in the chapter on the handling of food safety accidents, requiring the health administrative department at or above the county level to promptly investigate and deal with the relevant agricultural administration, quality supervision, industrial and commercial administration and food and drug supervision and management departments after receiving the report of food safety accidents, and order food producers and operators to recall, stop business and destroy the food and its raw materials that are confirmed to be contaminated according to regulations.

????Abolish the system of exemption from inspection and strengthen food inspection

????Sanlu group was once the largest milk powder producer in China, and Sanlu milk powder was once one of the assured products announced by the General Administration of Quality Supervision, Inspection and Quarantine, and it was also a product exempt from inspection. But this "Sanlu incident" just shows that exemption from inspection is not equal to safety, and the failure of inspection means will bring serious consequences.

????Therefore, it is clearly stipulated in the third draft of the Food Safety Law that the food safety supervision and management department shall not exempt the food from inspection, and legalize the previous measures of abolishing the inspection exemption in the State Council.

????The draft also stipulates that quality supervision, industry and commerce administration and food and drug supervision and administration departments at or above the county level shall conduct regular or irregular sampling inspection of food.

????Relevant persons said that food inspection is an important part of food safety, and the regulatory authorities cannot give up their responsibilities. In the face of quality and safety, big and small brands should be treated equally, and the supervision of big brands should be even stricter, because the greater the influence of brand products, the more people will be affected.

????Food safety standards should be based on ensuring public health.

????It is understood that China’s current food safety standards include agricultural product quality and safety standards, food hygiene standards, food quality standards and some industry standards.

????In view of the phenomenon of non-uniform standards, some members of the National People’s Congress Standing Committee (NPCSC) proposed that the draft food safety law should clearly define the basic principles for formulating food safety standards. To this end, the third draft of the draft stipulates that food safety standards should be formulated with the aim of ensuring public health, and the content should be scientific, reasonable, safe and reliable.

????According to the draft food safety law, the health administrative department of the State Council will be responsible for formulating and publishing uniform and mandatory food safety standards.

????Relevant persons pointed out that the above provisions can prevent the standards from fighting with each other on the one hand, and avoid some standards that have no effect on ensuring food safety on the other. According to reports, some existing regulations, such as steamed bread must be round and the diameter of Yuanxiao must be several centimeters, have no effect on food safety.

????Strengthen the supervision of small food workshops and vendors

????In this "Sanlu incident", some large dairy enterprises have developed rapidly in production scale, and their own milk sources are difficult to meet production, so they buy a large number of milk sources from farmers and retail investors, which makes the quality difficult to supervise.

????Not only in the dairy industry, but also in the whole food industry, a large number of scattered food workshops and vendors are the places with the most hidden dangers of food safety accidents.

????The draft food safety law has stipulated that the state shall implement a licensing system for food production and operation. However, food production enterprises above designated size account for about 25% of the total number of production enterprises in China, and small food workshops account for the majority, which cannot be extended by the licensing system. Therefore, it is necessary to strengthen daily supervision and management to ensure food safety.

????Some members of the National People’s Congress Standing Committee (NPCSC) suggested that the draft food safety law should clarify that the government should strengthen supervision over small food workshops and vendors.

????Therefore, in the third draft of the Food Safety Law, the relevant provisions were revised as follows: small food production and processing workshops and food vendors engaged in food production and marketing activities should meet the food safety requirements stipulated in this Law that are appropriate to the scale and conditions of their production and marketing, and ensure that the food they produce and market is hygienic, non-toxic and harmless, and the relevant departments should strengthen supervision and management. The specific management measures shall be formulated by the standing committees of the people’s congresses of provinces, autonomous regions and municipalities directly under the Central Government in accordance with this Law.

??? Emphasize the reporting system and improve the handling mechanism of food safety accidents

????The reporting system has relatively perfect provisions in many laws, including the Emergency Response Law, and even stipulates how many hours the report must be carried out. However, the relevant parties in the "Sanlu incident" did not implement this system.

????In order to solve this problem, the third draft of the draft food safety law specifically reiterated the reporting system: units that have food safety accidents should be disposed of immediately to prevent the accidents from expanding. The accident unit and the unit receiving the patient for treatment shall report to the county health administrative department where the accident occurred in time.

????The draft also clearly pointed out that the food safety supervision department should immediately notify the health administrative department when it finds or receives a report of food safety accidents. In the event of a major food safety accident, the health administrative department shall report it step by step according to the regulations. No unit or individual may conceal, falsely report or delay reporting food safety accidents, and may not destroy relevant evidence.

????According to the provisions of the draft, the people’s governments at or above the county level should set up a food safety accident handling command organization and start an emergency plan; If food safety accidents involving more than two provinces are involved, the administrative department of health of the State Council shall organize an accident responsibility investigation.

????The draft food safety law clearly stipulates the accountability system. The draft stipulates that those who cause personal, property or other damage shall be liable for compensation according to law, and those who constitute a crime shall be investigated for criminal responsibility according to law.